| | Hannibal, MO | Midland, MI | United States |
| Population | 17,165 | 42,425 | 329,725,481 |
| Female Population | 52.5% | 51.0% | 50.5% |
| Male Population | 47.5% | 49.0% | 49.5% |
| Median Age | 38 | 37.9 | 38.4 |
| space3 | | | |
| Population - 2010 | 17,771 | 41,880 | 309,327,143 |
| Population - 2000 | 17,757 | 41,685 | 285,036,114 |
| Population - 1990 | 18,004 | 38,053 | 251,960,433 |
| Pop. 2000 to Now | -2.9% | 0.2% | 15.6% |
| Pop. 1990 to Now | -4.2% | 9.8% | 30.8% |
| space4 | | | |
| Population Density | 1,090.9 | 1,234.8 | 93.4 |
| Land Area | 15.7 | 34.4 | 3,531,905.4 |
| Water Area | 0.5 | 2.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Hannibal, MO | Midland, MI | United States |
| Age 0 to 4 | 6.3% | 5.6% | 5.9% |
| Age 5 to 9 | 6.1% | 6.6% | 6.1% |
| Age 10 to 14 | 7.8% | 5.8% | 6.6% |
| Age 15 to 17 | 3.5% | 3.7% | 3.9% |
| Age 18 to 20 | 5.1% | 4.4% | 4.0% |
| Age 21 to 24 | 5.9% | 5.7% | 5.2% |
| Age 25 to 34 | 11.8% | 14.3% | 13.8% |
| Age 35 to 44 | 10.3% | 12.1% | 12.9% |
| Age 45 to 54 | 10.7% | 10.8% | 12.6% |
| Age 55 to 59 | 5.6% | 6.9% | 6.7% |
| Age 60 to 64 | 8.2% | 6.0% | 6.3% |
| Age 65 to 74 | 10.7% | 9.0% | 9.6% |
| Age 75 to 84 | 4.7% | 5.5% | 4.5% |
| Age 85 and over | 3.1% | 3.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | Hannibal, MO | Midland, MI | United States |
| White | 87.1% | 87.4% | 59.4% |
| Black | 6.1% | 2.4% | 12.2% |
| Asian | 0.5% | 3.1% | 5.6% |
| Native American | 0.2% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.2% | 0.1% | 0.2% |
| Other | 0.3% | 0.3% | 0.4% |
| Two or More Races | 2.7% | 2.2% | 3.2% |
| Hispanic | 3.0% | 4.2% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Hannibal, MO | Midland, MI | United States |
| Married Population | 45.5% | 52.7% | 49.8% |
| Currently Married | 44.2% | 51.4% | 48.0% |
| Married but Separated | 1.3% | 1.4% | 1.8% |
| Single Population | 54.5% | 47.3% | 50.2% |
| Never Married | 31.9% | 29.1% | 33.8% |
| Divorced | 15.2% | 12.3% | 10.8% |
| Widowed | 7.4% | 5.9% | 5.6% |
| space5 | | | |
| Household Size | 2.28 | 2.32 | 2.60 |
| Households | 6,988 | 17,813 | 124,010,992 |
| Family Households | 4,195 | 10,781 | 80,755,759 |
| Married couple, w/children | 26.5% | 34.5% | 30.5% |
| Married couple, no children | 42.2% | 43.9% | 42.9% |
| Non Family Households | 2,793 | 7,032 | 43,255,233 |
| Single householder, w/children | 24.6% | 13.7% | 15.8% |
| Single householder, no children | 6.7% | 7.9% | 10.8% |