| | Harrisburg, PA | St. Johns, AZ | United States |
| Population | 49,969 | 3,416 | 329,725,481 |
| Female Population | 51.5% | 43.1% | 50.5% |
| Male Population | 48.5% | 56.9% | 49.5% |
| Median Age | 31.6 | 26.9 | 38.4 |
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| Population - 2010 | 49,513 | 3,494 | 309,327,143 |
| Population - 2000 | 48,950 | 3,269 | 285,036,114 |
| Population - 1990 | 52,376 | 3,294 | 251,960,433 |
| Pop. 2000 to Now | 0.8% | 7.9% | 15.6% |
| Pop. 1990 to Now | -5.8% | 7.0% | 30.8% |
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| Population Density | 6,154.6 | 131.9 | 93.4 |
| Land Area | 8.1 | 25.9 | 3,531,905.4 |
| Water Area | 3.7 | 0.2 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Harrisburg, PA | St. Johns, AZ | United States |
| Age 0 to 4 | 8.6% | 6.1% | 5.9% |
| Age 5 to 9 | 8.1% | 8.5% | 6.1% |
| Age 10 to 14 | 8.6% | 11.8% | 6.6% |
| Age 15 to 17 | 3.6% | 5.4% | 3.9% |
| Age 18 to 20 | 3.4% | 11.4% | 4.0% |
| Age 21 to 24 | 5.7% | 5.2% | 5.2% |
| Age 25 to 34 | 17.4% | 9.0% | 13.8% |
| Age 35 to 44 | 11.1% | 9.2% | 12.9% |
| Age 45 to 54 | 11.2% | 12.0% | 12.6% |
| Age 55 to 59 | 6.7% | 0.8% | 6.7% |
| Age 60 to 64 | 4.8% | 10.6% | 6.3% |
| Age 65 to 74 | 6.5% | 8.3% | 9.6% |
| Age 75 to 84 | 3.4% | 1.5% | 4.5% |
| Age 85 and over | 0.9% | 0.1% | 1.9% |
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| Race | | | |
| | Harrisburg, PA | St. Johns, AZ | United States |
| White | 24.4% | 44.9% | 59.4% |
| Black | 44.0% | 5.4% | 12.2% |
| Asian | 2.6% | 0.0% | 5.6% |
| Native American | 0.2% | 8.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.1% | 0.0% | 0.2% |
| Other | 0.4% | 0.3% | 0.4% |
| Two or More Races | 3.3% | 1.2% | 3.2% |
| Hispanic | 25.1% | 39.5% | 18.4% |
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| Marriage & Family | | | |
| | Harrisburg, PA | St. Johns, AZ | United States |
| Married Population | 31.4% | 47.7% | 49.8% |
| Currently Married | 27.3% | 45.9% | 48.0% |
| Married but Separated | 4.2% | 1.8% | 1.8% |
| Single Population | 68.6% | 52.3% | 50.2% |
| Never Married | 49.4% | 35.9% | 33.8% |
| Divorced | 13.0% | 14.9% | 10.8% |
| Widowed | 6.1% | 1.6% | 5.6% |
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| Household Size | 2.33 | 3.93 | 2.60 |
| Households | 20,953 | 841 | 124,010,992 |
| Family Households | 10,507 | 644 | 80,755,759 |
| Married couple, w/children | 15.0% | 33.5% | 30.5% |
| Married couple, no children | 26.1% | 31.2% | 42.9% |
| Non Family Households | 10,446 | 197 | 43,255,233 |
| Single householder, w/children | 40.0% | 18.6% | 15.8% |
| Single householder, no children | 18.9% | 16.6% | 10.8% |