| | Sanibel, FL | Nokomis, FL | United States |
| Population | 6,437 | 3,481 | 329,725,481 |
| Female Population | 52.1% | 42.6% | 50.5% |
| Male Population | 47.9% | 57.4% | 49.5% |
| Median Age | 68.2 | 51 | 38.4 |
| space3 | | | |
| Population - 2010 | 6,486 | 3,286 | 309,327,143 |
| Population - 2000 | 6,064 | 3,334 | 285,036,114 |
| Population - 1990 | 5,468 | 3,448 | 251,960,433 |
| Pop. 2000 to Now | 22.5% | 10.9% | 15.6% |
| Pop. 1990 to Now | 35.9% | 7.2% | 30.8% |
| space4 | | | |
| Population Density | 397.9 | 2,138.2 | 93.4 |
| Land Area | 16.2 | 1.6 | 3,531,905.4 |
| Water Area | 17.0 | 0.3 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Sanibel, FL | Nokomis, FL | United States |
| Age 0 to 4 | 0.4% | 3.7% | 5.9% |
| Age 5 to 9 | 0.8% | 0.6% | 6.1% |
| Age 10 to 14 | 0.9% | 2.2% | 6.6% |
| Age 15 to 17 | 0.4% | 6.8% | 3.9% |
| Age 18 to 20 | 0.5% | 4.5% | 4.0% |
| Age 21 to 24 | 1.7% | 2.6% | 5.2% |
| Age 25 to 34 | 3.3% | 8.6% | 13.8% |
| Age 35 to 44 | 2.4% | 9.9% | 12.9% |
| Age 45 to 54 | 5.8% | 16.1% | 12.6% |
| Age 55 to 59 | 11.2% | 7.1% | 6.7% |
| Age 60 to 64 | 12.7% | 12.1% | 6.3% |
| Age 65 to 74 | 37.1% | 19.4% | 9.6% |
| Age 75 to 84 | 19.4% | 4.4% | 4.5% |
| Age 85 and over | 3.4% | 1.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Sanibel, FL | Nokomis, FL | United States |
| White | 96.9% | 85.8% | 59.4% |
| Black | 0.3% | 1.5% | 12.2% |
| Asian | 0.8% | 4.1% | 5.6% |
| Native American | 0.0% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.3% | 0.0% | 0.4% |
| Two or More Races | 0.6% | 0.7% | 3.2% |
| Hispanic | 1.1% | 7.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Sanibel, FL | Nokomis, FL | United States |
| Married Population | 77.2% | 44.1% | 49.8% |
| Currently Married | 76.7% | 40.8% | 48.0% |
| Married but Separated | 0.5% | 3.3% | 1.8% |
| Single Population | 22.8% | 55.9% | 50.2% |
| Never Married | 7.8% | 30.0% | 33.8% |
| Divorced | 7.0% | 19.7% | 10.8% |
| Widowed | 8.0% | 6.2% | 5.6% |
| space5 | | | |
| Household Size | 1.85 | 1.82 | 2.60 |
| Households | 3,471 | 1,910 | 124,010,992 |
| Family Households | 2,406 | 899 | 80,755,759 |
| Married couple, w/children | 2.0% | 10.5% | 30.5% |
| Married couple, no children | 92.3% | 54.8% | 42.9% |
| Non Family Households | 1,065 | 1,011 | 43,255,233 |
| Single householder, w/children | 2.9% | 23.9% | 15.8% |
| Single householder, no children | 2.8% | 10.8% | 10.8% |