Living in 63775 Perryville, MO is an enjoyable experience as the town provides a comfortable and laid-back atmosphere. Located in the heart of Cape Girardeau County and nestled among rolling hills, Perryville offers plenty of outdoor activities to enjoy including fishing, hiking, boating, and more. The small town feel is highlighted by friendly locals and the warm hospitality that comes with living in a rural area. Downtown Perryville has a quaint Main Street lined with unique storefronts and eateries offering delicious local cuisine. Whether you’re looking for a peaceful rural escape or simply want to explore the region’s history, culture, or attractions – Perryville has something for everyone!