| School Name | Grades | Address | Zip | Phone | County | Type | District Name |
| Center for Alternative Education | 4-12 | 900 East Third Street
Picayune, MS | 39466 | (601) 799-0684 | Pearl River | public | Picayune School District |
| Nicholson Elementary School | PK-6 | 1887 Hwy 11 South
Picayune, MS | 39466 | (601) 798-6309 | Pearl River | public | Picayune School District |
| Picayune Junior High School | 7-8 | 702 Goodyear Blvd
Picayune, MS | 39466 | (601) 798-5449 | Pearl River | public | Picayune School District |
| Picayune Memorial High School | 9-12 | 800 Fifth Ave
Picayune, MS | 39466 | (601) 798-1380 | Pearl River | public | Picayune School District |
| PMHS Career & Technology Center | 9-12 | 600 Goodyear Blvd
Picayune, MS | 39466 | (601) 798-7601 | Pearl River | public | Picayune School District |
| Roseland Park Baptist Church Aca | PK-8 | 2132 Hwy 11 N
Picayune, MS | 39466 | (601) 798-3918 | Pearl River | private | |
| Roseland Park Elementary School | K-6 | 1610 Gilcrease St
Picayune, MS | 39466 | (601) 798-6824 | Pearl River | public | Picayune School District |
| South Side Elementary School | 3-6 | 1500 Rosa St
Picayune, MS | 39466 | (601) 798-1105 | Pearl River | public | Picayune School District |
| South Side Lower Elementary School | PK-2 | 400 South Beech St
Picayune, MS | 39466 | (601) 799-0683 | Pearl River | public | Picayune School District |
| St. Francis Academy - St. Michael's Campus | n/a | P.O. Box 640
Picayune, MS | 39466 | (601) 799-5750 | Pearl River | private | |
| Union Baptist Academy | PK-10 | 1628 W Union Rd
Picayune, MS | 39466 | (601) 798-6470 | Pearl River | private | |
| West Hancock Elementary School | K-5 | 23350 Hwy 43
Picayune, MS | 39466 | (228) 586-6054 | Pearl River | public | Hancock County School District |
| West Side Elementary School | K-6 | 111 Kirkwood St
Picayune, MS | 39466 | (601) 798-3625 | Pearl River | public | Picayune School District |
