| School Name | Grades | Address | Zip | Phone | County | Type | District Name |
| Alma Schrader Elementary School | K-4 | 1360 Randol
Cape Girardeau, MO | 63701 | (573) 335-5310 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Blanchard Elementary School | K-4 | 1829 N Sprigg St
Cape Girardeau, MO | 63701 | (573) 335-3030 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Cape Christian School | K-8 | 1855 Perryville Rd
Cape Girardeau, MO | 63701 | (573) 335-8333 | Cape Girardeau | private | |
| Cape Girardeau Car & Tech Center | 9-12 | 1080 S Silver Springs Rd
Cape Girardeau, MO | 63703 | (573) 334-0826 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Central High School | 9-12 | 1000 S Silver Springs Rd
Cape Girardeau, MO | 63701 | (573) 335-8228 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Central Junior High School | 7-8 | 205 Caruthers
Cape Girardeau, MO | 63701 | (573) 334-2923 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Central Middle School | 5-6 | 1900 Thilenius
Cape Girardeau, MO | 63701 | (573) 334-6281 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Clippard Elementary School | K-4 | 2880 Hopper Rd
Cape Girardeau, MO | 63701 | (573) 334-5720 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Deer Creek Christian Academy | PK-5, 7-8 | 2039 Cape Lacroix Rd
Cape Girardeau, MO | 63701 | (573) 332-8966 | Cape Girardeau | private | |
| Eagle Ridge Christian School | PK-12 | 4210 State Highway K
Cape Girardeau, MO | 63701 | (573) 339-1335 | Cape Girardeau | private | |
| Franklin Elementary School | K-4 | 215 N Louisiana
Cape Girardeau, MO | 63701 | (573) 335-5456 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Gordonville Attendance Center | K-2 | 653 State Hwy Z
Cape Girardeau, MO | 63701 | (573) 243-9580 | Cape Girardeau | public | Jackson R-II School District |
| Jefferson Elementary School | K-4 | 520 S Minnesota
Cape Girardeau, MO | 63703 | (573) 334-2030 | Cape Girardeau | public | Cape Girardeau 63 School District |
| Nell Holcomb Elementary School | K-8 | 6547 State Hwy 177
Cape Girardeau, MO | 63701 | (573) 334-3644 | Cape Girardeau | public | Nell Holcomb R-IV School District |
| Notre Dame Regional High School | 9-12 | 265 Notre Dame Dr
Cape Girardeau, MO | 63701 | (573) 335-6772 | Cape Girardeau | private | |
| St. Mary Cathedral School | K-8 | 210 S Sprigg St
Cape Girardeau, MO | 63703 | (573) 335-3840 | Cape Girardeau | private | |
| St. Vincent De Paul Elementary School | K-8 | 1919 Ritter Dr
Cape Girardeau, MO | 63701 | (573) 334-9594 | Cape Girardeau | private | |
| Trinity Lutheran School | PK-8 | 55 N Pacific St
Cape Girardeau, MO | 63701 | (573) 335-5046 | Cape Girardeau | private | |
