| School Name | Grades | Address | Zip | Phone | County | Type | District Name |
| Agape Christian School | K-12 | 3191 Oak Grove Road
Poplar Bluff, MO | 63901 | (573) 785-1387 | Butler | private | |
| Eugene Field Elementary School | 1-4 | 711 Nickey St
Poplar Bluff, MO | 63901 | (573) 785-4047 | Butler | public | Poplar Bluff R-I School District |
| Lake Road Elementary School | 1-4 | 986 Hwy Aa
Poplar Bluff, MO | 63901 | (573) 785-4392 | Butler | public | Poplar Bluff R-I School District |
| Mark Twain Kindergarten Center | K | 1235 N Main St
Poplar Bluff, MO | 63901 | (573) 785-4905 | Butler | public | Poplar Bluff R-I School District |
| O'Neal Elementary School | 1-4 | 2300 Baugh Ln
Poplar Bluff, MO | 63901 | (573) 785-3037 | Butler | public | Poplar Bluff R-I School District |
| Oak Grove Elementary School | 1-4 | 3297 Oak Grove Rd
Poplar Bluff, MO | 63901 | (573) 785-6589 | Butler | public | Poplar Bluff R-I School District |
| Poplar Bluff 5th & 6th Center | 5-6 | 3209 Oak Grove Rd
Poplar Bluff, MO | 63901 | (573) 785-5566 | Butler | public | Poplar Bluff R-I School District |
| Poplar Bluff High School | 9-12 | 1300 Victory Ln
Poplar Bluff, MO | 63901 | (573) 785-6471 | Butler | public | Poplar Bluff R-I School District |
| Poplar Bluff Junior High School | 7-8 | 550 N Westwood
Poplar Bluff, MO | 63901 | (573) 785-5602 | Butler | public | Poplar Bluff R-I School District |
| Poplar Bluff Tech. Career Center | 10-12 | 3203 Oak Grove Rd
Poplar Bluff, MO | 63901 | (573) 785-2248 | Butler | public | Poplar Bluff R-I School District |
| Sacred Heart School | PK-8 | 111 N 8th St
Poplar Bluff, MO | 63901 | (573) 785-5836 | Butler | private | |
| Southern MO Christian School | K-12 | 3001 Warrior Lane
Poplar Bluff, MO | 63901 | (573) 686-1155 | Butler | private | |
| Westwood Baptist Academy | PK-12 | 419 County Road 5231
Poplar Bluff, MO | 63901 | (573) 785-2922 | Butler | private | |
| Zion Lutheran | n/a | 450 N Main St
Poplar Bluff, MO | 63901 | (573) 785-6112 | Butler | private | |
