Caruthersville, MO is a small city located in Pemiscot County with a population of 6,383 according to the US Census Bureau. It is located along the Mississippi River and has plenty of outdoor activities such as fishing, boating, and camping right near its shores. The area also boasts historic sites like the Caruthersville Historic Downtown District and Northward Merchantile Museum & Cotton Gin which are great places to explore local history. Shopping options are limited but there are plenty of restaurants to check out, including some delicious local favorites. With friendly residents, a vibrant cultural scene, and an array of outdoor activities for all ages and interests, living in Caruthersville is sure to be an enjoyable experience.