| | Seneca, PA | State College, PA | United States |
| Population | 883 | 40,352 | 329,725,481 |
| Female Population | 48.3% | 46.3% | 50.5% |
| Male Population | 51.8% | 53.7% | 49.5% |
| Median Age | 53.2 | 21.5 | 38.4 |
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| Population - 2010 | 1,051 | 41,993 | 309,327,143 |
| Population - 2000 | 966 | 38,420 | 285,036,114 |
| Population - 1990 | 1,029 | 38,923 | 251,960,433 |
| Pop. 2000 to Now | 20.0% | 7.7% | 15.6% |
| Pop. 1990 to Now | 12.6% | 6.3% | 30.8% |
| space4 | | | |
| Population Density | 392.8 | 8,856.9 | 93.4 |
| Land Area | 2.2 | 4.6 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Seneca, PA | State College, PA | United States |
| Age 0 to 4 | 3.7% | 1.7% | 5.9% |
| Age 5 to 9 | 0.8% | 1.9% | 6.1% |
| Age 10 to 14 | 9.3% | 1.5% | 6.6% |
| Age 15 to 17 | 8.9% | 1.4% | 3.9% |
| Age 18 to 20 | 2.4% | 36.0% | 4.0% |
| Age 21 to 24 | 0.0% | 26.4% | 5.2% |
| Age 25 to 34 | 2.5% | 10.9% | 13.8% |
| Age 35 to 44 | 13.4% | 5.1% | 12.9% |
| Age 45 to 54 | 11.3% | 4.1% | 12.6% |
| Age 55 to 59 | 4.3% | 2.2% | 6.7% |
| Age 60 to 64 | 12.0% | 2.8% | 6.3% |
| Age 65 to 74 | 21.1% | 3.0% | 9.6% |
| Age 75 to 84 | 6.8% | 1.8% | 4.5% |
| Age 85 and over | 3.5% | 1.2% | 1.9% |
| space1 | | | |
| Race | | | |
| | Seneca, PA | State College, PA | United States |
| White | 96.8% | 80.2% | 59.4% |
| Black | 0.0% | 3.2% | 12.2% |
| Asian | 1.4% | 10.0% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 1.8% | 2.4% | 3.2% |
| Hispanic | 0.0% | 4.1% | 18.4% |
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| Marriage & Family | | | |
| | Seneca, PA | State College, PA | United States |
| Married Population | 62.3% | 16.9% | 49.8% |
| Currently Married | 62.3% | 16.4% | 48.0% |
| Married but Separated | 0.0% | 0.5% | 1.8% |
| Single Population | 37.7% | 83.1% | 50.2% |
| Never Married | 20.2% | 78.4% | 33.8% |
| Divorced | 11.3% | 2.8% | 10.8% |
| Widowed | 6.2% | 1.9% | 5.6% |
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| Household Size | 2.13 | 2.49 | 2.60 |
| Households | 415 | 11,352 | 124,010,992 |
| Family Households | 290 | 3,416 | 80,755,759 |
| Married couple, w/children | 28.6% | 31.7% | 30.5% |
| Married couple, no children | 53.1% | 48.4% | 42.9% |
| Non Family Households | 125 | 7,936 | 43,255,233 |
| Single householder, w/children | 15.9% | 12.7% | 15.8% |
| Single householder, no children | 2.4% | 7.2% | 10.8% |