| | Cowley, WY | Afton, WY | United States |
| Population | 688 | 2,181 | 329,725,481 |
| Female Population | 55.4% | 56.3% | 50.5% |
| Male Population | 44.6% | 43.7% | 49.5% |
| Median Age | 30.6 | 32.8 | 38.4 |
| space3 | | | |
| Population - 2010 | 661 | 1,923 | 309,327,143 |
| Population - 2000 | 560 | 1,818 | 285,036,114 |
| Population - 1990 | 477 | 1,394 | 251,960,433 |
| Pop. 2000 to Now | 33.4% | 13.9% | 15.6% |
| Pop. 1990 to Now | 56.6% | 48.6% | 30.8% |
| space4 | | | |
| Population Density | 811.3 | 505.8 | 93.4 |
| Land Area | 0.8 | 4.3 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Cowley, WY | Afton, WY | United States |
| Age 0 to 4 | 11.6% | 8.9% | 5.9% |
| Age 5 to 9 | 11.5% | 6.4% | 6.1% |
| Age 10 to 14 | 8.0% | 5.8% | 6.6% |
| Age 15 to 17 | 4.4% | 5.0% | 3.9% |
| Age 18 to 20 | 4.1% | 8.7% | 4.0% |
| Age 21 to 24 | 3.9% | 5.0% | 5.2% |
| Age 25 to 34 | 16.7% | 12.2% | 13.8% |
| Age 35 to 44 | 10.8% | 7.8% | 12.9% |
| Age 45 to 54 | 5.5% | 10.1% | 12.6% |
| Age 55 to 59 | 5.1% | 10.4% | 6.7% |
| Age 60 to 64 | 3.6% | 3.2% | 6.3% |
| Age 65 to 74 | 11.3% | 8.7% | 9.6% |
| Age 75 to 84 | 2.9% | 5.0% | 4.5% |
| Age 85 and over | 0.6% | 2.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | Cowley, WY | Afton, WY | United States |
| White | 83.7% | 83.6% | 59.4% |
| Black | 5.7% | 0.0% | 12.2% |
| Asian | 2.3% | 0.4% | 5.6% |
| Native American | 0.9% | 0.8% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.4% | 0.0% | 0.4% |
| Two or More Races | 5.1% | 5.5% | 3.2% |
| Hispanic | 1.9% | 9.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Cowley, WY | Afton, WY | United States |
| Married Population | 75.5% | 50.0% | 49.8% |
| Currently Married | 75.5% | 48.5% | 48.0% |
| Married but Separated | 0.0% | 1.5% | 1.8% |
| Single Population | 24.5% | 50.0% | 50.2% |
| Never Married | 16.2% | 35.2% | 33.8% |
| Divorced | 2.1% | 8.6% | 10.8% |
| Widowed | 6.1% | 6.3% | 5.6% |
| space5 | | | |
| Household Size | 3.53 | 2.56 | 2.60 |
| Households | 195 | 839 | 124,010,992 |
| Family Households | 166 | 528 | 80,755,759 |
| Married couple, w/children | 40.4% | 35.8% | 30.5% |
| Married couple, no children | 50.6% | 43.0% | 42.9% |
| Non Family Households | 29 | 311 | 43,255,233 |
| Single householder, w/children | 6.0% | 14.4% | 15.8% |
| Single householder, no children | 3.0% | 6.8% | 10.8% |