| | Fort Madison, IA | Fort Wayne, IN | United States |
| Population | 10,340 | 262,676 | 329,725,481 |
| Female Population | 45.6% | 51.2% | 50.5% |
| Male Population | 54.4% | 48.8% | 49.5% |
| Median Age | 42.9 | 35.1 | 38.4 |
| space3 | | | |
| Population - 2010 | 11,076 | 254,134 | 309,327,143 |
| Population - 2000 | 10,715 | 205,727 | 285,036,114 |
| Population - 1990 | 11,618 | 173,072 | 251,960,433 |
| Pop. 2000 to Now | -4.2% | 32.4% | 15.6% |
| Pop. 1990 to Now | -11.7% | 57.4% | 30.8% |
| space4 | | | |
| Population Density | 1,069.3 | 2,374.5 | 93.4 |
| Land Area | 9.7 | 110.6 | 3,531,905.4 |
| Water Area | 3.6 | 0.2 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Fort Madison, IA | Fort Wayne, IN | United States |
| Age 0 to 4 | 4.1% | 7.0% | 5.9% |
| Age 5 to 9 | 6.1% | 6.8% | 6.1% |
| Age 10 to 14 | 5.6% | 6.7% | 6.6% |
| Age 15 to 17 | 5.0% | 4.1% | 3.9% |
| Age 18 to 20 | 3.0% | 4.0% | 4.0% |
| Age 21 to 24 | 4.9% | 6.2% | 5.2% |
| Age 25 to 34 | 11.1% | 15.1% | 13.8% |
| Age 35 to 44 | 13.8% | 12.2% | 12.9% |
| Age 45 to 54 | 13.0% | 11.7% | 12.6% |
| Age 55 to 59 | 7.3% | 6.4% | 6.7% |
| Age 60 to 64 | 6.8% | 5.7% | 6.3% |
| Age 65 to 74 | 11.8% | 8.4% | 9.6% |
| Age 75 to 84 | 4.0% | 3.7% | 4.5% |
| Age 85 and over | 3.6% | 1.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Fort Madison, IA | Fort Wayne, IN | United States |
| White | 86.9% | 65.3% | 59.4% |
| Black | 4.4% | 15.0% | 12.2% |
| Asian | 0.0% | 5.5% | 5.6% |
| Native American | 0.1% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.1% | 0.3% | 0.4% |
| Two or More Races | 2.4% | 4.3% | 3.2% |
| Hispanic | 6.2% | 9.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Fort Madison, IA | Fort Wayne, IN | United States |
| Married Population | 48.4% | 45.7% | 49.8% |
| Currently Married | 47.5% | 44.2% | 48.0% |
| Married but Separated | 0.9% | 1.5% | 1.8% |
| Single Population | 51.6% | 54.3% | 50.2% |
| Never Married | 30.5% | 36.1% | 33.8% |
| Divorced | 14.6% | 12.3% | 10.8% |
| Widowed | 6.5% | 5.9% | 5.6% |
| space5 | | | |
| Household Size | 2.20 | 2.42 | 2.60 |
| Households | 4,335 | 106,669 | 124,010,992 |
| Family Households | 2,585 | 63,566 | 80,755,759 |
| Married couple, w/children | 25.6% | 28.4% | 30.5% |
| Married couple, no children | 50.8% | 39.7% | 42.9% |
| Non Family Households | 1,750 | 43,103 | 43,255,233 |
| Single householder, w/children | 17.4% | 22.2% | 15.8% |
| Single householder, no children | 6.2% | 9.8% | 10.8% |