| | De Soto, IA | League City, TX | United States |
| Population | 1,037 | 111,847 | 329,725,481 |
| Female Population | 52.9% | 50.1% | 50.5% |
| Male Population | 47.1% | 49.9% | 49.5% |
| Median Age | 35.3 | 36.6 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,049 | 84,099 | 309,327,143 |
| Population - 2000 | 1,009 | 45,444 | 285,036,114 |
| Population - 1990 | 1,033 | 30,159 | 251,960,433 |
| Pop. 2000 to Now | 5.2% | 138.7% | 15.6% |
| Pop. 1990 to Now | 2.7% | 259.7% | 30.8% |
| space4 | | | |
| Population Density | 680.0 | 2,181.9 | 93.4 |
| Land Area | 1.5 | 51.3 | 3,531,905.4 |
| Water Area | 0.0 | 1.7 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | De Soto, IA | League City, TX | United States |
| Age 0 to 4 | 7.9% | 6.3% | 5.9% |
| Age 5 to 9 | 7.0% | 8.6% | 6.1% |
| Age 10 to 14 | 10.0% | 7.6% | 6.6% |
| Age 15 to 17 | 5.5% | 4.9% | 3.9% |
| Age 18 to 20 | 3.5% | 3.4% | 4.0% |
| Age 21 to 24 | 2.0% | 3.1% | 5.2% |
| Age 25 to 34 | 13.5% | 13.6% | 13.8% |
| Age 35 to 44 | 18.1% | 15.8% | 12.9% |
| Age 45 to 54 | 8.7% | 14.8% | 12.6% |
| Age 55 to 59 | 6.3% | 6.2% | 6.7% |
| Age 60 to 64 | 2.8% | 4.8% | 6.3% |
| Age 65 to 74 | 10.0% | 6.5% | 9.6% |
| Age 75 to 84 | 3.5% | 3.1% | 4.5% |
| Age 85 and over | 1.2% | 1.4% | 1.9% |
| space1 | | | |
| Race | | | |
| | De Soto, IA | League City, TX | United States |
| White | 90.0% | 65.9% | 59.4% |
| Black | 0.0% | 7.8% | 12.2% |
| Asian | 3.8% | 6.3% | 5.6% |
| Native American | 0.9% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.2% | 0.4% |
| Two or More Races | 1.4% | 2.9% | 3.2% |
| Hispanic | 4.1% | 16.9% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | De Soto, IA | League City, TX | United States |
| Married Population | 62.1% | 62.0% | 49.8% |
| Currently Married | 62.1% | 61.0% | 48.0% |
| Married but Separated | 0.0% | 0.9% | 1.8% |
| Single Population | 37.9% | 38.0% | 50.2% |
| Never Married | 25.3% | 25.9% | 33.8% |
| Divorced | 8.2% | 8.8% | 10.8% |
| Widowed | 4.4% | 3.3% | 5.6% |
| space5 | | | |
| Household Size | 2.64 | 2.72 | 2.60 |
| Households | 393 | 40,964 | 124,010,992 |
| Family Households | 291 | 30,031 | 80,755,759 |
| Married couple, w/children | 40.9% | 45.5% | 30.5% |
| Married couple, no children | 38.8% | 39.0% | 42.9% |
| Non Family Households | 102 | 10,933 | 43,255,233 |
| Single householder, w/children | 13.4% | 8.6% | 15.8% |
| Single householder, no children | 6.9% | 6.9% | 10.8% |