| | Depew, OK | Cushing, OK | United States |
| Population | 400 | 8,201 | 329,725,481 |
| Female Population | 49.0% | 44.5% | 50.5% |
| Male Population | 51.0% | 55.5% | 49.5% |
| Median Age | 37.7 | 34.1 | 38.4 |
| space3 | | | |
| Population - 2010 | 479 | 7,830 | 309,327,143 |
| Population - 2000 | 564 | 8,371 | 285,036,114 |
| Population - 1990 | 502 | 7,218 | 251,960,433 |
| Pop. 2000 to Now | -15.6% | -9.4% | 15.6% |
| Pop. 1990 to Now | -5.2% | 5.0% | 30.8% |
| space4 | | | |
| Population Density | 968.5 | 1,051.4 | 93.4 |
| Land Area | 0.4 | 7.8 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Depew, OK | Cushing, OK | United States |
| Age 0 to 4 | 5.3% | 6.6% | 5.9% |
| Age 5 to 9 | 6.8% | 7.5% | 6.1% |
| Age 10 to 14 | 10.3% | 5.9% | 6.6% |
| Age 15 to 17 | 3.5% | 4.1% | 3.9% |
| Age 18 to 20 | 6.3% | 3.6% | 4.0% |
| Age 21 to 24 | 4.0% | 5.3% | 5.2% |
| Age 25 to 34 | 12.0% | 17.9% | 13.8% |
| Age 35 to 44 | 14.5% | 13.9% | 12.9% |
| Age 45 to 54 | 9.5% | 10.6% | 12.6% |
| Age 55 to 59 | 5.0% | 5.7% | 6.7% |
| Age 60 to 64 | 2.8% | 5.2% | 6.3% |
| Age 65 to 74 | 8.5% | 6.7% | 9.6% |
| Age 75 to 84 | 9.5% | 5.1% | 4.5% |
| Age 85 and over | 2.3% | 1.8% | 1.9% |
| space1 | | | |
| Race | | | |
| | Depew, OK | Cushing, OK | United States |
| White | 67.0% | 73.9% | 59.4% |
| Black | 4.8% | 5.0% | 12.2% |
| Asian | 0.0% | 0.3% | 5.6% |
| Native American | 17.8% | 7.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 9.5% | 7.3% | 3.2% |
| Hispanic | 1.0% | 6.0% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Depew, OK | Cushing, OK | United States |
| Married Population | 40.5% | 44.0% | 49.8% |
| Currently Married | 37.0% | 41.5% | 48.0% |
| Married but Separated | 3.5% | 2.5% | 1.8% |
| Single Population | 59.5% | 56.0% | 50.2% |
| Never Married | 25.4% | 32.7% | 33.8% |
| Divorced | 19.3% | 16.2% | 10.8% |
| Widowed | 14.8% | 7.1% | 5.6% |
| space5 | | | |
| Household Size | 2.25 | 2.52 | 2.60 |
| Households | 178 | 2,854 | 124,010,992 |
| Family Households | 121 | 1,798 | 80,755,759 |
| Married couple, w/children | 21.5% | 31.4% | 30.5% |
| Married couple, no children | 24.8% | 34.3% | 42.9% |
| Non Family Households | 57 | 1,056 | 43,255,233 |
| Single householder, w/children | 42.1% | 24.5% | 15.8% |
| Single householder, no children | 11.6% | 9.8% | 10.8% |