| | Guadalupe, AZ | Chandler, AZ | United States |
| Population | 5,334 | 272,439 | 329,725,481 |
| Female Population | 51.5% | 50.4% | 50.5% |
| Male Population | 48.5% | 49.6% | 49.5% |
| Median Age | 34.1 | 36.9 | 38.4 |
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| Population - 2010 | 5,529 | 236,459 | 309,327,143 |
| Population - 2000 | 5,228 | 176,581 | 285,036,114 |
| Population - 1990 | 5,458 | 90,533 | 251,960,433 |
| Pop. 2000 to Now | 28.1% | 50.3% | 15.6% |
| Pop. 1990 to Now | 22.7% | 193.2% | 30.8% |
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| Population Density | 6,634.3 | 4,192.6 | 93.4 |
| Land Area | 0.8 | 65.0 | 3,531,905.4 |
| Water Area | 0.0 | 0.1 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Guadalupe, AZ | Chandler, AZ | United States |
| Age 0 to 4 | 5.8% | 5.9% | 5.9% |
| Age 5 to 9 | 8.6% | 6.8% | 6.1% |
| Age 10 to 14 | 7.3% | 7.3% | 6.6% |
| Age 15 to 17 | 5.6% | 4.2% | 3.9% |
| Age 18 to 20 | 2.4% | 3.5% | 4.0% |
| Age 21 to 24 | 3.5% | 4.3% | 5.2% |
| Age 25 to 34 | 17.7% | 14.9% | 13.8% |
| Age 35 to 44 | 10.7% | 15.5% | 12.9% |
| Age 45 to 54 | 11.8% | 14.5% | 12.6% |
| Age 55 to 59 | 6.8% | 6.4% | 6.7% |
| Age 60 to 64 | 7.9% | 5.0% | 6.3% |
| Age 65 to 74 | 8.2% | 7.6% | 9.6% |
| Age 75 to 84 | 2.6% | 3.3% | 4.5% |
| Age 85 and over | 1.1% | 1.0% | 1.9% |
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| Race | | | |
| | Guadalupe, AZ | Chandler, AZ | United States |
| White | 3.5% | 56.4% | 59.4% |
| Black | 1.2% | 5.4% | 12.2% |
| Asian | 1.0% | 10.8% | 5.6% |
| Native American | 20.0% | 1.4% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.2% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 0.9% | 3.9% | 3.2% |
| Hispanic | 73.5% | 21.5% | 18.4% |
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| Marriage & Family | | | |
| | Guadalupe, AZ | Chandler, AZ | United States |
| Married Population | 43.9% | 52.7% | 49.8% |
| Currently Married | 40.5% | 51.6% | 48.0% |
| Married but Separated | 3.4% | 1.1% | 1.8% |
| Single Population | 56.1% | 47.3% | 50.2% |
| Never Married | 38.1% | 32.0% | 33.8% |
| Divorced | 14.8% | 12.1% | 10.8% |
| Widowed | 3.2% | 3.2% | 5.6% |
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| Household Size | 3.30 | 2.65 | 2.60 |
| Households | 1,614 | 102,568 | 124,010,992 |
| Family Households | 1,222 | 70,010 | 80,755,759 |
| Married couple, w/children | 20.8% | 36.4% | 30.5% |
| Married couple, no children | 36.4% | 38.8% | 42.9% |
| Non Family Households | 392 | 32,558 | 43,255,233 |
| Single householder, w/children | 26.1% | 15.3% | 15.8% |
| Single householder, no children | 16.7% | 9.4% | 10.8% |