| | Jeffersonville, IN | Andalusia, AL | United States |
| Population | 49,178 | 8,764 | 329,725,481 |
| Female Population | 50.8% | 53.5% | 50.5% |
| Male Population | 49.2% | 46.5% | 49.5% |
| Median Age | 37.9 | 39.6 | 38.4 |
| space3 | | | |
| Population - 2010 | 45,146 | 9,022 | 309,327,143 |
| Population - 2000 | 27,362 | 8,794 | 285,036,114 |
| Population - 1990 | 21,841 | 9,269 | 251,960,433 |
| Pop. 2000 to Now | 77.4% | -1.3% | 15.6% |
| Pop. 1990 to Now | 122.2% | -6.4% | 30.8% |
| space4 | | | |
| Population Density | 1,442.1 | 445.9 | 93.4 |
| Land Area | 34.1 | 19.7 | 3,531,905.4 |
| Water Area | 0.3 | 0.2 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Jeffersonville, IN | Andalusia, AL | United States |
| Age 0 to 4 | 6.2% | 7.4% | 5.9% |
| Age 5 to 9 | 6.0% | 6.8% | 6.1% |
| Age 10 to 14 | 6.5% | 4.6% | 6.6% |
| Age 15 to 17 | 3.8% | 4.8% | 3.9% |
| Age 18 to 20 | 2.9% | 3.4% | 4.0% |
| Age 21 to 24 | 4.3% | 4.6% | 5.2% |
| Age 25 to 34 | 15.6% | 11.1% | 13.8% |
| Age 35 to 44 | 12.9% | 12.2% | 12.9% |
| Age 45 to 54 | 12.4% | 10.5% | 12.6% |
| Age 55 to 59 | 7.4% | 6.0% | 6.7% |
| Age 60 to 64 | 6.4% | 8.8% | 6.3% |
| Age 65 to 74 | 9.7% | 11.0% | 9.6% |
| Age 75 to 84 | 4.4% | 4.7% | 4.5% |
| Age 85 and over | 1.5% | 4.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Jeffersonville, IN | Andalusia, AL | United States |
| White | 74.7% | 71.9% | 59.4% |
| Black | 11.6% | 23.2% | 12.2% |
| Asian | 1.6% | 0.0% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.6% | 0.0% | 0.4% |
| Two or More Races | 6.1% | 1.8% | 3.2% |
| Hispanic | 5.4% | 3.2% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Jeffersonville, IN | Andalusia, AL | United States |
| Married Population | 47.8% | 37.6% | 49.8% |
| Currently Married | 46.5% | 35.4% | 48.0% |
| Married but Separated | 1.3% | 2.2% | 1.8% |
| Single Population | 52.2% | 62.4% | 50.2% |
| Never Married | 30.5% | 34.3% | 33.8% |
| Divorced | 15.1% | 17.5% | 10.8% |
| Widowed | 6.6% | 10.7% | 5.6% |
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| Household Size | 2.46 | 2.65 | 2.60 |
| Households | 19,618 | 3,148 | 124,010,992 |
| Family Households | 12,629 | 1,928 | 80,755,759 |
| Married couple, w/children | 27.5% | 20.8% | 30.5% |
| Married couple, no children | 43.0% | 38.0% | 42.9% |
| Non Family Households | 6,989 | 1,220 | 43,255,233 |
| Single householder, w/children | 18.4% | 26.2% | 15.8% |
| Single householder, no children | 11.1% | 15.0% | 10.8% |