| | Masaryktown, FL | Matlacha, FL | United States |
| Population | 778 | 827 | 329,725,481 |
| Female Population | 59.0% | 58.8% | 50.5% |
| Male Population | 41.0% | 41.2% | 49.5% |
| Median Age | 49.5 | 64.6 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,130 | 754 | 309,327,143 |
| Population - 2000 | 920 | 735 | 285,036,114 |
| Population - 1990 | 422 | 802 | 251,960,433 |
| Pop. 2000 to Now | 5.2% | 8.3% | 15.6% |
| Pop. 1990 to Now | 129.4% | -0.8% | 30.8% |
| space4 | | | |
| Population Density | 743.8 | 4,135.0 | 93.4 |
| Land Area | 1.0 | 0.2 | 3,531,905.4 |
| Water Area | 0.0 | 0.5 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Masaryktown, FL | Matlacha, FL | United States |
| Age 0 to 4 | 5.0% | 0.0% | 5.9% |
| Age 5 to 9 | 4.6% | 0.0% | 6.1% |
| Age 10 to 14 | 9.1% | 0.0% | 6.6% |
| Age 15 to 17 | 0.8% | 10.9% | 3.9% |
| Age 18 to 20 | 0.0% | 0.8% | 4.0% |
| Age 21 to 24 | 0.0% | 1.7% | 5.2% |
| Age 25 to 34 | 15.3% | 2.2% | 13.8% |
| Age 35 to 44 | 10.0% | 0.0% | 12.9% |
| Age 45 to 54 | 18.9% | 18.3% | 12.6% |
| Age 55 to 59 | 4.2% | 5.6% | 6.7% |
| Age 60 to 64 | 4.2% | 11.5% | 6.3% |
| Age 65 to 74 | 22.1% | 45.5% | 9.6% |
| Age 75 to 84 | 4.6% | 3.6% | 4.5% |
| Age 85 and over | 1.0% | 0.0% | 1.9% |
| space1 | | | |
| Race | | | |
| | Masaryktown, FL | Matlacha, FL | United States |
| White | 92.4% | 93.8% | 59.4% |
| Black | 0.8% | 0.0% | 12.2% |
| Asian | 0.0% | 0.8% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 0.0% | 1.2% | 3.2% |
| Hispanic | 6.8% | 4.1% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Masaryktown, FL | Matlacha, FL | United States |
| Married Population | 50.9% | 64.1% | 49.8% |
| Currently Married | 50.9% | 60.9% | 48.0% |
| Married but Separated | 0.0% | 3.1% | 1.8% |
| Single Population | 49.1% | 35.9% | 50.2% |
| Never Married | 26.3% | 17.1% | 33.8% |
| Divorced | 14.1% | 13.8% | 10.8% |
| Widowed | 8.7% | 5.1% | 5.6% |
| space5 | | | |
| Household Size | 1.97 | 1.85 | 2.60 |
| Households | 395 | 446 | 124,010,992 |
| Family Households | 187 | 251 | 80,755,759 |
| Married couple, w/children | 26.7% | 47.8% | 30.5% |
| Married couple, no children | 58.8% | 47.8% | 42.9% |
| Non Family Households | 208 | 195 | 43,255,233 |
| Single householder, w/children | 14.4% | 4.4% | 15.8% |
| Single householder, no children | 0.0% | 0.0% | 10.8% |