| | Mayo, MD | Centreville, VA | United States |
| Population | 8,197 | 73,064 | 329,725,481 |
| Female Population | 49.8% | 50.1% | 50.5% |
| Male Population | 50.2% | 49.9% | 49.5% |
| Median Age | 38 | 36.8 | 38.4 |
| space3 | | | |
| Population - 2010 | 7,776 | 72,406 | 309,327,143 |
| Population - 2000 | 3,153 | 48,661 | 285,036,114 |
| Population - 1990 | 2,537 | 26,585 | 251,960,433 |
| Pop. 2000 to Now | 184.1% | 54.7% | 15.6% |
| Pop. 1990 to Now | 253.1% | 183.1% | 30.8% |
| space4 | | | |
| Population Density | 1,458.3 | 6,117.7 | 93.4 |
| Land Area | 5.6 | 11.9 | 3,531,905.4 |
| Water Area | 3.8 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Mayo, MD | Centreville, VA | United States |
| Age 0 to 4 | 9.3% | 5.8% | 5.9% |
| Age 5 to 9 | 3.2% | 7.6% | 6.1% |
| Age 10 to 14 | 4.7% | 6.4% | 6.6% |
| Age 15 to 17 | 4.8% | 4.0% | 3.9% |
| Age 18 to 20 | 5.8% | 3.7% | 4.0% |
| Age 21 to 24 | 4.8% | 5.8% | 5.2% |
| Age 25 to 34 | 14.9% | 14.0% | 13.8% |
| Age 35 to 44 | 9.1% | 15.6% | 12.9% |
| Age 45 to 54 | 17.2% | 14.3% | 12.6% |
| Age 55 to 59 | 6.7% | 6.8% | 6.7% |
| Age 60 to 64 | 5.6% | 6.4% | 6.3% |
| Age 65 to 74 | 7.8% | 6.3% | 9.6% |
| Age 75 to 84 | 4.4% | 2.6% | 4.5% |
| Age 85 and over | 1.5% | 0.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | Mayo, MD | Centreville, VA | United States |
| White | 92.0% | 42.5% | 59.4% |
| Black | 3.5% | 6.9% | 12.2% |
| Asian | 1.4% | 28.6% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.5% | 0.4% |
| Two or More Races | 2.3% | 4.7% | 3.2% |
| Hispanic | 0.8% | 16.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Mayo, MD | Centreville, VA | United States |
| Married Population | 61.9% | 58.0% | 49.8% |
| Currently Married | 60.5% | 56.7% | 48.0% |
| Married but Separated | 1.4% | 1.3% | 1.8% |
| Single Population | 38.1% | 42.0% | 50.2% |
| Never Married | 28.1% | 31.5% | 33.8% |
| Divorced | 5.4% | 7.8% | 10.8% |
| Widowed | 4.6% | 2.7% | 5.6% |
| space5 | | | |
| Household Size | 2.76 | 2.97 | 2.60 |
| Households | 2,968 | 24,617 | 124,010,992 |
| Family Households | 2,351 | 18,608 | 80,755,759 |
| Married couple, w/children | 41.7% | 42.1% | 30.5% |
| Married couple, no children | 41.6% | 39.5% | 42.9% |
| Non Family Households | 617 | 6,009 | 43,255,233 |
| Single householder, w/children | 6.9% | 9.7% | 15.8% |
| Single householder, no children | 9.8% | 8.7% | 10.8% |