| | Medford, OK | Helena, OK | United States |
| Population | 924 | 1,398 | 329,725,481 |
| Female Population | 49.1% | 14.3% | 50.5% |
| Male Population | 50.9% | 85.7% | 49.5% |
| Median Age | 43.5 | 47.3 | 38.4 |
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| Population - 2010 | 999 | 1,406 | 309,327,143 |
| Population - 2000 | 1,172 | 443 | 285,036,114 |
| Population - 1990 | 1,172 | 1,043 | 251,960,433 |
| Pop. 2000 to Now | -19.5% | 219.9% | 15.6% |
| Pop. 1990 to Now | -19.5% | 35.9% | 30.8% |
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| Population Density | 858.7 | 3,788.6 | 93.4 |
| Land Area | 1.1 | 0.4 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Medford, OK | Helena, OK | United States |
| Age 0 to 4 | 4.4% | 1.1% | 5.9% |
| Age 5 to 9 | 3.0% | 1.6% | 6.1% |
| Age 10 to 14 | 6.7% | 1.4% | 6.6% |
| Age 15 to 17 | 3.1% | 1.4% | 3.9% |
| Age 18 to 20 | 1.7% | 0.0% | 4.0% |
| Age 21 to 24 | 7.4% | 1.1% | 5.2% |
| Age 25 to 34 | 13.0% | 3.4% | 13.8% |
| Age 35 to 44 | 11.9% | 32.3% | 12.9% |
| Age 45 to 54 | 12.2% | 25.8% | 12.6% |
| Age 55 to 59 | 4.3% | 7.9% | 6.7% |
| Age 60 to 64 | 6.2% | 7.4% | 6.3% |
| Age 65 to 74 | 10.6% | 11.0% | 9.6% |
| Age 75 to 84 | 7.3% | 4.9% | 4.5% |
| Age 85 and over | 8.1% | 0.9% | 1.9% |
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| Race | | | |
| | Medford, OK | Helena, OK | United States |
| White | 92.7% | 65.7% | 59.4% |
| Black | 0.4% | 9.5% | 12.2% |
| Asian | 0.1% | 0.0% | 5.6% |
| Native American | 0.1% | 8.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.4% | 0.3% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 3.1% | 8.2% | 3.2% |
| Hispanic | 3.0% | 7.7% | 18.4% |
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| Marriage & Family | | | |
| | Medford, OK | Helena, OK | United States |
| Married Population | 42.9% | 28.2% | 49.8% |
| Currently Married | 39.6% | 25.9% | 48.0% |
| Married but Separated | 3.3% | 2.3% | 1.8% |
| Single Population | 57.1% | 71.8% | 50.2% |
| Never Married | 29.5% | 30.1% | 33.8% |
| Divorced | 12.5% | 35.8% | 10.8% |
| Widowed | 15.1% | 5.8% | 5.6% |
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| Household Size | 2.29 | 2.76 | 2.60 |
| Households | 379 | 144 | 124,010,992 |
| Family Households | 190 | 107 | 80,755,759 |
| Married couple, w/children | 21.1% | 41.1% | 30.5% |
| Married couple, no children | 60.0% | 53.3% | 42.9% |
| Non Family Households | 189 | 37 | 43,255,233 |
| Single householder, w/children | 12.1% | 3.7% | 15.8% |
| Single householder, no children | 6.8% | 1.9% | 10.8% |