| | Middlesex, NY | Italy, NY | United States |
| Population | 1,249 | 919 | 329,725,481 |
| Female Population | 51.1% | 49.7% | 50.5% |
| Male Population | 48.9% | 50.3% | 49.5% |
| Median Age | 56.6 | 47.6 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,500 | 1,155 | 309,327,143 |
| Population - 2000 | 1,345 | 1,087 | 285,036,114 |
| Population - 1990 | 1,249 | 1,120 | 251,960,433 |
| Pop. 2000 to Now | 8.0% | 5.2% | 15.6% |
| Pop. 1990 to Now | 16.3% | 2.1% | 30.8% |
| space4 | | | |
| Population Density | 40.5 | 22.9 | 93.4 |
| Land Area | 30.9 | 40.1 | 3,531,905.4 |
| Water Area | 3.2 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Middlesex, NY | Italy, NY | United States |
| Age 0 to 4 | 3.4% | 5.3% | 5.9% |
| Age 5 to 9 | 5.5% | 2.7% | 6.1% |
| Age 10 to 14 | 2.7% | 3.8% | 6.6% |
| Age 15 to 17 | 6.5% | 1.9% | 3.9% |
| Age 18 to 20 | 3.1% | 2.2% | 4.0% |
| Age 21 to 24 | 3.2% | 4.2% | 5.2% |
| Age 25 to 34 | 7.4% | 9.6% | 13.8% |
| Age 35 to 44 | 8.3% | 16.5% | 12.9% |
| Age 45 to 54 | 6.2% | 15.7% | 12.6% |
| Age 55 to 59 | 20.4% | 6.6% | 6.7% |
| Age 60 to 64 | 9.4% | 11.3% | 6.3% |
| Age 65 to 74 | 14.3% | 13.5% | 9.6% |
| Age 75 to 84 | 4.1% | 4.8% | 4.5% |
| Age 85 and over | 5.3% | 1.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Middlesex, NY | Italy, NY | United States |
| White | 93.6% | 95.5% | 59.4% |
| Black | 2.6% | 0.0% | 12.2% |
| Asian | 0.4% | 0.0% | 5.6% |
| Native American | 0.0% | 0.7% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 1.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 1.9% | 2.8% | 3.2% |
| Hispanic | 1.4% | 0.0% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Middlesex, NY | Italy, NY | United States |
| Married Population | 44.9% | 59.5% | 49.8% |
| Currently Married | 44.6% | 56.0% | 48.0% |
| Married but Separated | 0.3% | 3.5% | 1.8% |
| Single Population | 55.1% | 40.5% | 50.2% |
| Never Married | 25.8% | 22.0% | 33.8% |
| Divorced | 19.9% | 14.2% | 10.8% |
| Widowed | 9.3% | 4.3% | 5.6% |
| space5 | | | |
| Household Size | 2.67 | 2.48 | 2.60 |
| Households | 452 | 370 | 124,010,992 |
| Family Households | 330 | 248 | 80,755,759 |
| Married couple, w/children | 13.9% | 19.4% | 30.5% |
| Married couple, no children | 56.1% | 66.1% | 42.9% |
| Non Family Households | 122 | 122 | 43,255,233 |
| Single householder, w/children | 12.1% | 8.1% | 15.8% |
| Single householder, no children | 17.9% | 6.5% | 10.8% |