| | Middletown, VA | Portsmouth, VA | United States |
| Population | 1,608 | 97,454 | 329,725,481 |
| Female Population | 53.0% | 51.6% | 50.5% |
| Male Population | 47.0% | 48.4% | 49.5% |
| Median Age | 39.5 | 35.5 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,272 | 95,457 | 309,327,143 |
| Population - 2000 | 1,015 | 100,565 | 285,036,114 |
| Population - 1990 | 1,061 | 103,907 | 251,960,433 |
| Pop. 2000 to Now | 40.3% | -5.4% | 15.6% |
| Pop. 1990 to Now | 34.2% | -8.5% | 30.8% |
| space4 | | | |
| Population Density | 2,074.8 | 2,926.5 | 93.4 |
| Land Area | 0.8 | 33.3 | 3,531,905.4 |
| Water Area | 0.0 | 13.4 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Middletown, VA | Portsmouth, VA | United States |
| Age 0 to 4 | 7.2% | 7.3% | 5.9% |
| Age 5 to 9 | 3.8% | 6.3% | 6.1% |
| Age 10 to 14 | 7.0% | 6.4% | 6.6% |
| Age 15 to 17 | 4.8% | 3.4% | 3.9% |
| Age 18 to 20 | 4.5% | 3.7% | 4.0% |
| Age 21 to 24 | 3.6% | 5.5% | 5.2% |
| Age 25 to 34 | 14.2% | 16.5% | 13.8% |
| Age 35 to 44 | 15.9% | 12.3% | 12.9% |
| Age 45 to 54 | 11.8% | 11.2% | 12.6% |
| Age 55 to 59 | 8.0% | 6.6% | 6.7% |
| Age 60 to 64 | 6.5% | 5.9% | 6.3% |
| Age 65 to 74 | 6.9% | 8.9% | 9.6% |
| Age 75 to 84 | 5.1% | 4.0% | 4.5% |
| Age 85 and over | 0.7% | 1.8% | 1.9% |
| space1 | | | |
| Race | | | |
| | Middletown, VA | Portsmouth, VA | United States |
| White | 83.7% | 36.5% | 59.4% |
| Black | 5.3% | 51.8% | 12.2% |
| Asian | 1.2% | 1.5% | 5.6% |
| Native American | 0.0% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 2.9% | 4.7% | 3.2% |
| Hispanic | 6.8% | 4.8% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Middletown, VA | Portsmouth, VA | United States |
| Married Population | 37.8% | 41.0% | 49.8% |
| Currently Married | 32.7% | 37.6% | 48.0% |
| Married but Separated | 5.1% | 3.5% | 1.8% |
| Single Population | 62.2% | 59.0% | 50.2% |
| Never Married | 33.3% | 38.6% | 33.8% |
| Divorced | 21.6% | 13.8% | 10.8% |
| Widowed | 7.3% | 6.6% | 5.6% |
| space5 | | | |
| Household Size | 2.64 | 2.43 | 2.60 |
| Households | 609 | 38,553 | 124,010,992 |
| Family Households | 401 | 23,005 | 80,755,759 |
| Married couple, w/children | 17.7% | 23.6% | 30.5% |
| Married couple, no children | 31.9% | 34.7% | 42.9% |
| Non Family Households | 208 | 15,548 | 43,255,233 |
| Single householder, w/children | 35.4% | 25.6% | 15.8% |
| Single householder, no children | 15.0% | 16.1% | 10.8% |