| | Missouri Valley, IA | Blair, NE | United States |
| Population | 2,683 | 7,725 | 329,725,481 |
| Female Population | 53.0% | 52.5% | 50.5% |
| Male Population | 47.0% | 47.5% | 49.5% |
| Median Age | 39.5 | 39.2 | 38.4 |
| space3 | | | |
| Population - 2010 | 2,829 | 7,648 | 309,327,143 |
| Population - 2000 | 2,992 | 7,512 | 285,036,114 |
| Population - 1990 | 2,888 | 6,860 | 251,960,433 |
| Pop. 2000 to Now | -13.9% | 5.8% | 15.6% |
| Pop. 1990 to Now | -10.8% | 15.9% | 30.8% |
| space4 | | | |
| Population Density | 830.4 | 1,402.3 | 93.4 |
| Land Area | 3.2 | 5.5 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Missouri Valley, IA | Blair, NE | United States |
| Age 0 to 4 | 5.1% | 7.1% | 5.9% |
| Age 5 to 9 | 7.3% | 5.9% | 6.1% |
| Age 10 to 14 | 8.9% | 8.3% | 6.6% |
| Age 15 to 17 | 2.7% | 5.9% | 3.9% |
| Age 18 to 20 | 4.7% | 4.0% | 4.0% |
| Age 21 to 24 | 5.4% | 4.8% | 5.2% |
| Age 25 to 34 | 10.3% | 9.1% | 13.8% |
| Age 35 to 44 | 12.8% | 13.5% | 12.9% |
| Age 45 to 54 | 13.9% | 10.7% | 12.6% |
| Age 55 to 59 | 4.2% | 7.7% | 6.7% |
| Age 60 to 64 | 6.1% | 6.7% | 6.3% |
| Age 65 to 74 | 8.6% | 9.3% | 9.6% |
| Age 75 to 84 | 7.2% | 4.5% | 4.5% |
| Age 85 and over | 2.7% | 2.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | Missouri Valley, IA | Blair, NE | United States |
| White | 94.4% | 94.1% | 59.4% |
| Black | 0.0% | 0.9% | 12.2% |
| Asian | 0.0% | 0.1% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.6% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 4.0% | 1.5% | 3.2% |
| Hispanic | 1.6% | 2.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Missouri Valley, IA | Blair, NE | United States |
| Married Population | 44.2% | 56.7% | 49.8% |
| Currently Married | 39.2% | 55.0% | 48.0% |
| Married but Separated | 4.9% | 1.7% | 1.8% |
| Single Population | 55.9% | 43.3% | 50.2% |
| Never Married | 28.8% | 29.8% | 33.8% |
| Divorced | 14.6% | 7.7% | 10.8% |
| Widowed | 12.4% | 5.8% | 5.6% |
| space5 | | | |
| Household Size | 2.31 | 2.49 | 2.60 |
| Households | 1,125 | 3,009 | 124,010,992 |
| Family Households | 610 | 1,978 | 80,755,759 |
| Married couple, w/children | 28.2% | 37.3% | 30.5% |
| Married couple, no children | 38.5% | 44.1% | 42.9% |
| Non Family Households | 515 | 1,031 | 43,255,233 |
| Single householder, w/children | 23.0% | 17.6% | 15.8% |
| Single householder, no children | 10.3% | 1.0% | 10.8% |