| | Monticello, MS | Wesson, MS | United States |
| Population | 1,411 | 2,224 | 329,725,481 |
| Female Population | 64.9% | 52.3% | 50.5% |
| Male Population | 35.2% | 47.8% | 49.5% |
| Median Age | 38.7 | 21 | 38.4 |
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| Population - 2010 | 1,566 | 1,916 | 309,327,143 |
| Population - 2000 | 1,726 | 1,693 | 285,036,114 |
| Population - 1990 | 1,755 | 1,510 | 251,960,433 |
| Pop. 2000 to Now | -16.2% | 9.2% | 15.6% |
| Pop. 1990 to Now | -17.6% | 22.5% | 30.8% |
| space4 | | | |
| Population Density | 338.3 | 499.7 | 93.4 |
| Land Area | 4.2 | 4.5 | 3,531,905.4 |
| Water Area | 0.1 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Monticello, MS | Wesson, MS | United States |
| Age 0 to 4 | 12.3% | 5.0% | 5.9% |
| Age 5 to 9 | 9.1% | 9.0% | 6.1% |
| Age 10 to 14 | 3.7% | 8.8% | 6.6% |
| Age 15 to 17 | 5.0% | 3.1% | 3.9% |
| Age 18 to 20 | 2.4% | 24.1% | 4.0% |
| Age 21 to 24 | 3.6% | 3.9% | 5.2% |
| Age 25 to 34 | 9.6% | 12.4% | 13.8% |
| Age 35 to 44 | 9.4% | 4.6% | 12.9% |
| Age 45 to 54 | 13.8% | 10.0% | 12.6% |
| Age 55 to 59 | 2.6% | 5.9% | 6.7% |
| Age 60 to 64 | 5.0% | 3.0% | 6.3% |
| Age 65 to 74 | 11.4% | 5.8% | 9.6% |
| Age 75 to 84 | 7.9% | 3.7% | 4.5% |
| Age 85 and over | 4.0% | 0.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | Monticello, MS | Wesson, MS | United States |
| White | 61.3% | 75.8% | 59.4% |
| Black | 31.8% | 17.6% | 12.2% |
| Asian | 1.5% | 0.0% | 5.6% |
| Native American | 2.3% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 2.9% | 0.4% |
| Two or More Races | 3.1% | 2.4% | 3.2% |
| Hispanic | 0.0% | 1.3% | 18.4% |
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| Marriage & Family | | | |
| | Monticello, MS | Wesson, MS | United States |
| Married Population | 41.5% | 36.6% | 49.8% |
| Currently Married | 40.5% | 32.6% | 48.0% |
| Married but Separated | 1.0% | 4.0% | 1.8% |
| Single Population | 58.5% | 63.4% | 50.2% |
| Never Married | 33.3% | 52.3% | 33.8% |
| Divorced | 14.5% | 5.9% | 10.8% |
| Widowed | 10.7% | 5.2% | 5.6% |
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| Household Size | 2.20 | 2.92 | 2.60 |
| Households | 642 | 594 | 124,010,992 |
| Family Households | 309 | 448 | 80,755,759 |
| Married couple, w/children | 29.8% | 24.8% | 30.5% |
| Married couple, no children | 36.9% | 31.9% | 42.9% |
| Non Family Households | 333 | 146 | 43,255,233 |
| Single householder, w/children | 27.5% | 33.0% | 15.8% |
| Single householder, no children | 5.8% | 10.3% | 10.8% |