| | Palo Alto, CA | Sugar Land, TX | United States |
| Population | 68,624 | 110,272 | 329,725,481 |
| Female Population | 51.6% | 50.2% | 50.5% |
| Male Population | 48.4% | 49.8% | 49.5% |
| Median Age | 41.8 | 42 | 38.4 |
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| Population - 2010 | 64,506 | 108,269 | 309,327,143 |
| Population - 2000 | 58,598 | 63,328 | 285,036,114 |
| Population - 1990 | 55,900 | 24,529 | 251,960,433 |
| Pop. 2000 to Now | 14.4% | 86.1% | 15.6% |
| Pop. 1990 to Now | 19.9% | 380.6% | 30.8% |
| space4 | | | |
| Population Density | 2,875.2 | 2,723.8 | 93.4 |
| Land Area | 23.9 | 40.5 | 3,531,905.4 |
| Water Area | 1.9 | 2.4 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Palo Alto, CA | Sugar Land, TX | United States |
| Age 0 to 4 | 4.7% | 4.4% | 5.9% |
| Age 5 to 9 | 5.6% | 6.4% | 6.1% |
| Age 10 to 14 | 7.6% | 7.1% | 6.6% |
| Age 15 to 17 | 5.0% | 4.8% | 3.9% |
| Age 18 to 20 | 2.8% | 2.9% | 4.0% |
| Age 21 to 24 | 3.7% | 4.4% | 5.2% |
| Age 25 to 34 | 12.2% | 10.7% | 13.8% |
| Age 35 to 44 | 12.1% | 13.2% | 12.9% |
| Age 45 to 54 | 14.7% | 14.8% | 12.6% |
| Age 55 to 59 | 7.4% | 7.1% | 6.7% |
| Age 60 to 64 | 5.6% | 7.7% | 6.3% |
| Age 65 to 74 | 8.3% | 10.8% | 9.6% |
| Age 75 to 84 | 6.0% | 4.1% | 4.5% |
| Age 85 and over | 4.2% | 1.6% | 1.9% |
| space1 | | | |
| Race | | | |
| | Palo Alto, CA | Sugar Land, TX | United States |
| White | 50.0% | 39.0% | 59.4% |
| Black | 2.1% | 7.0% | 12.2% |
| Asian | 35.0% | 38.0% | 5.6% |
| Native American | 0.1% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.1% | 0.2% | 0.2% |
| Other | 0.4% | 0.5% | 0.4% |
| Two or More Races | 5.4% | 3.0% | 3.2% |
| Hispanic | 7.0% | 12.0% | 18.4% |
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| Marriage & Family | | | |
| | Palo Alto, CA | Sugar Land, TX | United States |
| Married Population | 58.5% | 64.1% | 49.8% |
| Currently Married | 57.8% | 63.1% | 48.0% |
| Married but Separated | 0.7% | 1.0% | 1.8% |
| Single Population | 41.5% | 35.9% | 50.2% |
| Never Married | 29.6% | 25.1% | 33.8% |
| Divorced | 7.1% | 6.4% | 10.8% |
| Widowed | 4.8% | 4.4% | 5.6% |
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| Household Size | 2.62 | 2.96 | 2.60 |
| Households | 26,007 | 37,122 | 124,010,992 |
| Family Households | 17,570 | 29,642 | 80,755,759 |
| Married couple, w/children | 43.2% | 40.2% | 30.5% |
| Married couple, no children | 43.7% | 47.3% | 42.9% |
| Non Family Households | 8,437 | 7,480 | 43,255,233 |
| Single householder, w/children | 6.7% | 5.8% | 15.8% |
| Single householder, no children | 6.5% | 6.7% | 10.8% |