| | Parkston, SD | Santee, NE | United States |
| Population | 1,761 | 320 | 329,725,481 |
| Female Population | 47.3% | 51.3% | 50.5% |
| Male Population | 52.7% | 48.8% | 49.5% |
| Median Age | 37.1 | 23.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,514 | 335 | 309,327,143 |
| Population - 2000 | 1,674 | 302 | 285,036,114 |
| Population - 1990 | 1,572 | 365 | 251,960,433 |
| Pop. 2000 to Now | -13.0% | 11.9% | 15.6% |
| Pop. 1990 to Now | -7.4% | -7.4% | 30.8% |
| space4 | | | |
| Population Density | 1,351.5 | 567.4 | 93.4 |
| Land Area | 1.3 | 0.6 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Parkston, SD | Santee, NE | United States |
| Age 0 to 4 | 9.4% | 13.4% | 5.9% |
| Age 5 to 9 | 8.1% | 14.1% | 6.1% |
| Age 10 to 14 | 8.9% | 10.0% | 6.6% |
| Age 15 to 17 | 4.8% | 6.3% | 3.9% |
| Age 18 to 20 | 1.4% | 3.1% | 4.0% |
| Age 21 to 24 | 3.4% | 6.3% | 5.2% |
| Age 25 to 34 | 11.0% | 13.4% | 13.8% |
| Age 35 to 44 | 14.0% | 8.1% | 12.9% |
| Age 45 to 54 | 7.3% | 7.8% | 12.6% |
| Age 55 to 59 | 5.2% | 0.3% | 6.7% |
| Age 60 to 64 | 7.3% | 7.2% | 6.3% |
| Age 65 to 74 | 11.6% | 9.4% | 9.6% |
| Age 75 to 84 | 3.7% | 0.6% | 4.5% |
| Age 85 and over | 4.1% | 0.0% | 1.9% |
| space1 | | | |
| Race | | | |
| | Parkston, SD | Santee, NE | United States |
| White | 92.9% | 4.4% | 59.4% |
| Black | 0.0% | 0.6% | 12.2% |
| Asian | 0.0% | 0.3% | 5.6% |
| Native American | 0.5% | 81.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.3% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 2.8% | 2.2% | 3.2% |
| Hispanic | 3.8% | 10.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Parkston, SD | Santee, NE | United States |
| Married Population | 55.5% | 32.0% | 49.8% |
| Currently Married | 55.5% | 30.0% | 48.0% |
| Married but Separated | 0.0% | 2.0% | 1.8% |
| Single Population | 44.5% | 68.0% | 50.2% |
| Never Married | 21.0% | 50.0% | 33.8% |
| Divorced | 18.0% | 7.0% | 10.8% |
| Widowed | 5.5% | 11.0% | 5.6% |
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| Household Size | 2.35 | 3.29 | 2.60 |
| Households | 729 | 96 | 124,010,992 |
| Family Households | 462 | 64 | 80,755,759 |
| Married couple, w/children | 30.1% | 34.4% | 30.5% |
| Married couple, no children | 48.3% | 10.9% | 42.9% |
| Non Family Households | 267 | 32 | 43,255,233 |
| Single householder, w/children | 15.4% | 50.0% | 15.8% |
| Single householder, no children | 6.3% | 4.7% | 10.8% |