| | Poplar Bluff, MO | Bloomington, IN | United States |
| Population | 16,318 | 80,064 | 329,725,481 |
| Female Population | 52.5% | 49.8% | 50.5% |
| Male Population | 47.5% | 50.3% | 49.5% |
| Median Age | 37.2 | 24 | 38.4 |
| space3 | | | |
| Population - 2010 | 17,035 | 80,625 | 309,327,143 |
| Population - 2000 | 16,651 | 69,291 | 285,036,114 |
| Population - 1990 | 16,996 | 60,633 | 251,960,433 |
| Pop. 2000 to Now | 0.9% | 23.5% | 15.6% |
| Pop. 1990 to Now | -1.1% | 41.2% | 30.8% |
| space4 | | | |
| Population Density | 1,242.0 | 3,443.5 | 93.4 |
| Land Area | 13.1 | 23.3 | 3,531,905.4 |
| Water Area | 0.1 | 0.2 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Poplar Bluff, MO | Bloomington, IN | United States |
| Age 0 to 4 | 7.5% | 3.5% | 5.9% |
| Age 5 to 9 | 6.8% | 3.0% | 6.1% |
| Age 10 to 14 | 6.0% | 2.7% | 6.6% |
| Age 15 to 17 | 5.2% | 2.3% | 3.9% |
| Age 18 to 20 | 3.4% | 23.1% | 4.0% |
| Age 21 to 24 | 4.3% | 18.0% | 5.2% |
| Age 25 to 34 | 13.6% | 14.7% | 13.8% |
| Age 35 to 44 | 11.4% | 8.9% | 12.9% |
| Age 45 to 54 | 9.7% | 6.7% | 12.6% |
| Age 55 to 59 | 5.2% | 3.4% | 6.7% |
| Age 60 to 64 | 7.1% | 3.7% | 6.3% |
| Age 65 to 74 | 10.0% | 5.9% | 9.6% |
| Age 75 to 84 | 7.3% | 2.5% | 4.5% |
| Age 85 and over | 2.4% | 1.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | Poplar Bluff, MO | Bloomington, IN | United States |
| White | 79.9% | 77.3% | 59.4% |
| Black | 10.8% | 4.3% | 12.2% |
| Asian | 0.4% | 10.2% | 5.6% |
| Native American | 0.8% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.2% | 0.0% | 0.2% |
| Other | 0.1% | 0.1% | 0.4% |
| Two or More Races | 5.2% | 3.4% | 3.2% |
| Hispanic | 2.7% | 4.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Poplar Bluff, MO | Bloomington, IN | United States |
| Married Population | 38.4% | 25.9% | 49.8% |
| Currently Married | 35.1% | 25.0% | 48.0% |
| Married but Separated | 3.3% | 0.9% | 1.8% |
| Single Population | 61.6% | 74.1% | 50.2% |
| Never Married | 36.0% | 63.2% | 33.8% |
| Divorced | 17.9% | 7.8% | 10.8% |
| Widowed | 7.7% | 3.1% | 5.6% |
| space5 | | | |
| Household Size | 2.45 | 1.99 | 2.60 |
| Households | 6,390 | 32,599 | 124,010,992 |
| Family Households | 3,549 | 12,168 | 80,755,759 |
| Married couple, w/children | 17.2% | 23.5% | 30.5% |
| Married couple, no children | 41.2% | 46.3% | 42.9% |
| Non Family Households | 2,841 | 20,431 | 43,255,233 |
| Single householder, w/children | 32.5% | 19.5% | 15.8% |
| Single householder, no children | 9.1% | 10.7% | 10.8% |