| | Topeka, KS | Jefferson City, MO | United States |
| Population | 126,802 | 43,076 | 329,725,481 |
| Female Population | 51.8% | 47.8% | 50.5% |
| Male Population | 48.2% | 52.2% | 49.5% |
| Median Age | 38.1 | 37.8 | 38.4 |
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| Population - 2010 | 127,918 | 43,210 | 309,327,143 |
| Population - 2000 | 122,377 | 39,636 | 285,036,114 |
| Population - 1990 | 119,883 | 35,481 | 251,960,433 |
| Pop. 2000 to Now | 1.8% | 5.9% | 15.6% |
| Pop. 1990 to Now | 3.9% | 18.3% | 30.8% |
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| Population Density | 2,063.8 | 1,194.9 | 93.4 |
| Land Area | 61.4 | 36.1 | 3,531,905.4 |
| Water Area | 1.3 | 1.6 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Topeka, KS | Jefferson City, MO | United States |
| Age 0 to 4 | 6.1% | 6.2% | 5.9% |
| Age 5 to 9 | 7.1% | 5.7% | 6.1% |
| Age 10 to 14 | 5.9% | 5.3% | 6.6% |
| Age 15 to 17 | 3.7% | 3.4% | 3.9% |
| Age 18 to 20 | 3.7% | 4.3% | 4.0% |
| Age 21 to 24 | 6.0% | 5.6% | 5.2% |
| Age 25 to 34 | 13.2% | 15.0% | 13.8% |
| Age 35 to 44 | 12.3% | 14.3% | 12.9% |
| Age 45 to 54 | 11.1% | 12.1% | 12.6% |
| Age 55 to 59 | 6.3% | 6.1% | 6.7% |
| Age 60 to 64 | 6.5% | 6.8% | 6.3% |
| Age 65 to 74 | 10.0% | 9.0% | 9.6% |
| Age 75 to 84 | 5.3% | 4.2% | 4.5% |
| Age 85 and over | 2.7% | 1.9% | 1.9% |
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| Race | | | |
| | Topeka, KS | Jefferson City, MO | United States |
| White | 67.0% | 72.1% | 59.4% |
| Black | 10.1% | 18.8% | 12.2% |
| Asian | 1.6% | 2.5% | 5.6% |
| Native American | 0.7% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.4% | 0.7% | 0.4% |
| Two or More Races | 4.4% | 2.4% | 3.2% |
| Hispanic | 15.8% | 3.2% | 18.4% |
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| Marriage & Family | | | |
| | Topeka, KS | Jefferson City, MO | United States |
| Married Population | 44.8% | 43.1% | 49.8% |
| Currently Married | 43.3% | 42.2% | 48.0% |
| Married but Separated | 1.5% | 0.9% | 1.8% |
| Single Population | 55.2% | 56.9% | 50.2% |
| Never Married | 32.3% | 36.1% | 33.8% |
| Divorced | 15.4% | 15.8% | 10.8% |
| Widowed | 7.5% | 5.0% | 5.6% |
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| Household Size | 2.26 | 2.30 | 2.60 |
| Households | 54,257 | 16,655 | 124,010,992 |
| Family Households | 29,608 | 9,364 | 80,755,759 |
| Married couple, w/children | 28.6% | 27.0% | 30.5% |
| Married couple, no children | 39.7% | 46.3% | 42.9% |
| Non Family Households | 24,649 | 7,291 | 43,255,233 |
| Single householder, w/children | 20.2% | 20.0% | 15.8% |
| Single householder, no children | 11.5% | 6.7% | 10.8% |