| | Tuscola, TX | Big Spring, TX | United States |
| Population | 719 | 26,199 | 329,725,481 |
| Female Population | 50.6% | 42.8% | 50.5% |
| Male Population | 49.4% | 57.2% | 49.5% |
| Median Age | 35.6 | 36.2 | 38.4 |
| space3 | | | |
| Population - 2010 | 734 | 27,230 | 309,327,143 |
| Population - 2000 | 714 | 25,233 | 285,036,114 |
| Population - 1990 | 620 | 23,093 | 251,960,433 |
| Pop. 2000 to Now | 2.9% | 11.3% | 15.6% |
| Pop. 1990 to Now | 18.6% | 21.6% | 30.8% |
| space4 | | | |
| Population Density | 970.3 | 1,371.0 | 93.4 |
| Land Area | 0.7 | 19.1 | 3,531,905.4 |
| Water Area | 0.0 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Tuscola, TX | Big Spring, TX | United States |
| Age 0 to 4 | 5.7% | 6.3% | 5.9% |
| Age 5 to 9 | 8.5% | 5.6% | 6.1% |
| Age 10 to 14 | 10.6% | 6.0% | 6.6% |
| Age 15 to 17 | 5.0% | 3.0% | 3.9% |
| Age 18 to 20 | 4.2% | 6.4% | 4.0% |
| Age 21 to 24 | 0.4% | 4.6% | 5.2% |
| Age 25 to 34 | 13.6% | 16.2% | 13.8% |
| Age 35 to 44 | 13.8% | 15.4% | 12.9% |
| Age 45 to 54 | 10.0% | 14.5% | 12.6% |
| Age 55 to 59 | 4.7% | 5.7% | 6.7% |
| Age 60 to 64 | 7.5% | 4.9% | 6.3% |
| Age 65 to 74 | 4.6% | 6.4% | 9.6% |
| Age 75 to 84 | 6.8% | 3.6% | 4.5% |
| Age 85 and over | 4.6% | 1.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | Tuscola, TX | Big Spring, TX | United States |
| White | 82.8% | 39.5% | 59.4% |
| Black | 0.0% | 6.6% | 12.2% |
| Asian | 0.0% | 1.0% | 5.6% |
| Native American | 0.0% | 0.4% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.1% | 0.4% |
| Two or More Races | 6.7% | 2.9% | 3.2% |
| Hispanic | 10.6% | 49.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Tuscola, TX | Big Spring, TX | United States |
| Married Population | 57.5% | 46.2% | 49.8% |
| Currently Married | 54.5% | 42.8% | 48.0% |
| Married but Separated | 3.0% | 3.4% | 1.8% |
| Single Population | 42.5% | 53.8% | 50.2% |
| Never Married | 22.6% | 34.7% | 33.8% |
| Divorced | 11.5% | 13.0% | 10.8% |
| Widowed | 8.5% | 6.1% | 5.6% |
| space5 | | | |
| Household Size | 2.45 | 2.45 | 2.60 |
| Households | 293 | 9,022 | 124,010,992 |
| Family Households | 196 | 5,575 | 80,755,759 |
| Married couple, w/children | 38.8% | 30.1% | 30.5% |
| Married couple, no children | 40.3% | 37.0% | 42.9% |
| Non Family Households | 97 | 3,447 | 43,255,233 |
| Single householder, w/children | 13.3% | 24.7% | 15.8% |
| Single householder, no children | 7.7% | 8.2% | 10.8% |