| | Wilcox, NE | Holdrege, NE | United States |
| Population | 385 | 5,485 | 329,725,481 |
| Female Population | 47.3% | 51.2% | 50.5% |
| Male Population | 52.7% | 48.8% | 49.5% |
| Median Age | 37.4 | 40 | 38.4 |
| space3 | | | |
| Population - 2010 | 357 | 5,475 | 309,327,143 |
| Population - 2000 | 360 | 5,636 | 285,036,114 |
| Population - 1990 | 349 | 5,671 | 251,960,433 |
| Pop. 2000 to Now | -3.1% | -4.5% | 15.6% |
| Pop. 1990 to Now | 0.0% | -5.1% | 30.8% |
| space4 | | | |
| Population Density | 714.3 | 1,295.8 | 93.4 |
| Land Area | 0.5 | 4.2 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Wilcox, NE | Holdrege, NE | United States |
| Age 0 to 4 | 5.2% | 6.2% | 5.9% |
| Age 5 to 9 | 7.8% | 5.3% | 6.1% |
| Age 10 to 14 | 10.1% | 6.7% | 6.6% |
| Age 15 to 17 | 6.0% | 3.5% | 3.9% |
| Age 18 to 20 | 1.8% | 3.4% | 4.0% |
| Age 21 to 24 | 2.6% | 5.1% | 5.2% |
| Age 25 to 34 | 10.9% | 12.3% | 13.8% |
| Age 35 to 44 | 15.6% | 12.0% | 12.9% |
| Age 45 to 54 | 9.4% | 12.1% | 12.6% |
| Age 55 to 59 | 8.1% | 5.6% | 6.7% |
| Age 60 to 64 | 11.2% | 7.3% | 6.3% |
| Age 65 to 74 | 8.3% | 11.0% | 9.6% |
| Age 75 to 84 | 2.3% | 6.1% | 4.5% |
| Age 85 and over | 0.8% | 3.3% | 1.9% |
| space1 | | | |
| Race | | | |
| | Wilcox, NE | Holdrege, NE | United States |
| White | 88.3% | 87.8% | 59.4% |
| Black | 0.0% | 0.2% | 12.2% |
| Asian | 0.3% | 0.1% | 5.6% |
| Native American | 5.2% | 1.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 1.3% | 0.0% | 0.4% |
| Two or More Races | 4.4% | 2.1% | 3.2% |
| Hispanic | 0.5% | 8.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Wilcox, NE | Holdrege, NE | United States |
| Married Population | 54.1% | 52.8% | 49.8% |
| Currently Married | 51.7% | 52.0% | 48.0% |
| Married but Separated | 2.4% | 0.8% | 1.8% |
| Single Population | 45.9% | 47.2% | 50.2% |
| Never Married | 24.7% | 30.5% | 33.8% |
| Divorced | 14.9% | 11.0% | 10.8% |
| Widowed | 6.4% | 5.6% | 5.6% |
| space5 | | | |
| Household Size | 2.75 | 2.21 | 2.60 |
| Households | 140 | 2,419 | 124,010,992 |
| Family Households | 86 | 1,352 | 80,755,759 |
| Married couple, w/children | 41.9% | 28.6% | 30.5% |
| Married couple, no children | 51.2% | 49.9% | 42.9% |
| Non Family Households | 54 | 1,067 | 43,255,233 |
| Single householder, w/children | 3.5% | 17.8% | 15.8% |
| Single householder, no children | 3.5% | 3.6% | 10.8% |