| | Wintersville, OH | Louisville, OH | United States |
| Population | 3,892 | 9,497 | 329,725,481 |
| Female Population | 49.5% | 52.5% | 50.5% |
| Male Population | 50.5% | 47.5% | 49.5% |
| Median Age | 49.1 | 41.9 | 38.4 |
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| Population - 2010 | 3,914 | 9,260 | 309,327,143 |
| Population - 2000 | 4,067 | 8,904 | 285,036,114 |
| Population - 1990 | 4,102 | 8,087 | 251,960,433 |
| Pop. 2000 to Now | -10.4% | 5.3% | 15.6% |
| Pop. 1990 to Now | -11.1% | 16.0% | 30.8% |
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| Population Density | 1,245.4 | 1,677.6 | 93.4 |
| Land Area | 3.1 | 5.7 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Wintersville, OH | Louisville, OH | United States |
| Age 0 to 4 | 1.7% | 4.0% | 5.9% |
| Age 5 to 9 | 2.0% | 5.9% | 6.1% |
| Age 10 to 14 | 13.3% | 8.2% | 6.6% |
| Age 15 to 17 | 6.8% | 6.7% | 3.9% |
| Age 18 to 20 | 1.1% | 3.8% | 4.0% |
| Age 21 to 24 | 6.1% | 3.7% | 5.2% |
| Age 25 to 34 | 5.8% | 9.3% | 13.8% |
| Age 35 to 44 | 9.7% | 12.8% | 12.9% |
| Age 45 to 54 | 15.6% | 15.9% | 12.6% |
| Age 55 to 59 | 6.1% | 7.1% | 6.7% |
| Age 60 to 64 | 9.1% | 4.4% | 6.3% |
| Age 65 to 74 | 13.0% | 9.5% | 9.6% |
| Age 75 to 84 | 8.6% | 5.5% | 4.5% |
| Age 85 and over | 1.3% | 3.3% | 1.9% |
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| Race | | | |
| | Wintersville, OH | Louisville, OH | United States |
| White | 90.7% | 96.4% | 59.4% |
| Black | 5.3% | 0.3% | 12.2% |
| Asian | 0.0% | 0.6% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 2.1% | 1.0% | 3.2% |
| Hispanic | 1.9% | 1.6% | 18.4% |
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| Marriage & Family | | | |
| | Wintersville, OH | Louisville, OH | United States |
| Married Population | 44.1% | 53.5% | 49.8% |
| Currently Married | 42.6% | 53.0% | 48.0% |
| Married but Separated | 1.5% | 0.5% | 1.8% |
| Single Population | 55.9% | 46.5% | 50.2% |
| Never Married | 30.5% | 24.7% | 33.8% |
| Divorced | 16.6% | 15.0% | 10.8% |
| Widowed | 8.8% | 6.7% | 5.6% |
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| Household Size | 2.33 | 2.39 | 2.60 |
| Households | 1,633 | 3,935 | 124,010,992 |
| Family Households | 1,104 | 2,599 | 80,755,759 |
| Married couple, w/children | 26.3% | 32.4% | 30.5% |
| Married couple, no children | 35.5% | 44.2% | 42.9% |
| Non Family Households | 529 | 1,336 | 43,255,233 |
| Single householder, w/children | 23.6% | 16.2% | 15.8% |
| Single householder, no children | 14.7% | 7.1% | 10.8% |