| | Wynne, AR | Helena-West Helena, AR | United States |
| Population | 8,352 | 9,707 | 329,725,481 |
| Female Population | 53.2% | 54.3% | 50.5% |
| Male Population | 46.8% | 45.7% | 49.5% |
| Median Age | 37.7 | 36.3 | 38.4 |
| space3 | | | |
| Population - 2010 | 8,381 | 12,422 | 309,327,143 |
| Population - 2000 | 8,615 | 14,840 | 285,036,114 |
| Population - 1990 | 8,187 | 17,090 | 251,960,433 |
| Pop. 2000 to Now | -11.6% | -32.4% | 15.6% |
| Pop. 1990 to Now | -7.0% | -41.3% | 30.8% |
| space4 | | | |
| Population Density | 938.2 | 741.4 | 93.4 |
| Land Area | 8.9 | 13.1 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Wynne, AR | Helena-West Helena, AR | United States |
| Age 0 to 4 | 7.6% | 7.9% | 5.9% |
| Age 5 to 9 | 8.9% | 8.3% | 6.1% |
| Age 10 to 14 | 7.6% | 9.9% | 6.6% |
| Age 15 to 17 | 2.9% | 4.0% | 3.9% |
| Age 18 to 20 | 3.9% | 2.9% | 4.0% |
| Age 21 to 24 | 2.8% | 4.6% | 5.2% |
| Age 25 to 34 | 13.2% | 11.1% | 13.8% |
| Age 35 to 44 | 13.1% | 10.0% | 12.9% |
| Age 45 to 54 | 9.8% | 11.0% | 12.6% |
| Age 55 to 59 | 5.5% | 6.4% | 6.7% |
| Age 60 to 64 | 7.1% | 6.6% | 6.3% |
| Age 65 to 74 | 8.2% | 9.8% | 9.6% |
| Age 75 to 84 | 7.4% | 5.1% | 4.5% |
| Age 85 and over | 1.8% | 2.4% | 1.9% |
| space1 | | | |
| Race | | | |
| | Wynne, AR | Helena-West Helena, AR | United States |
| White | 62.2% | 19.8% | 59.4% |
| Black | 25.7% | 77.6% | 12.2% |
| Asian | 0.0% | 0.0% | 5.6% |
| Native American | 0.4% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 7.9% | 1.0% | 3.2% |
| Hispanic | 3.7% | 1.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Wynne, AR | Helena-West Helena, AR | United States |
| Married Population | 42.6% | 34.2% | 49.8% |
| Currently Married | 39.0% | 28.9% | 48.0% |
| Married but Separated | 3.6% | 5.3% | 1.8% |
| Single Population | 57.4% | 65.8% | 50.2% |
| Never Married | 28.4% | 42.5% | 33.8% |
| Divorced | 16.4% | 12.1% | 10.8% |
| Widowed | 12.6% | 11.3% | 5.6% |
| space5 | | | |
| Household Size | 2.63 | 2.66 | 2.60 |
| Households | 3,110 | 3,585 | 124,010,992 |
| Family Households | 1,904 | 2,017 | 80,755,759 |
| Married couple, w/children | 31.6% | 12.1% | 30.5% |
| Married couple, no children | 27.0% | 31.8% | 42.9% |
| Non Family Households | 1,206 | 1,568 | 43,255,233 |
| Single householder, w/children | 30.0% | 37.1% | 15.8% |
| Single householder, no children | 11.3% | 18.9% | 10.8% |