| | DeSoto, TX | Clarksville, TN | United States |
| Population | 55,761 | 163,518 | 329,725,481 |
| Female Population | 55.4% | 49.8% | 50.5% |
| Male Population | 44.6% | 50.2% | 49.5% |
| Median Age | 39.9 | 30 | 38.4 |
| space3 | | | |
| Population - 2010 | 49,357 | 133,483 | 309,327,143 |
| Population - 2000 | 37,646 | 103,455 | 285,036,114 |
| Population - 1990 | 30,544 | 75,494 | 251,960,433 |
| Pop. 2000 to Now | 40.6% | 55.9% | 15.6% |
| Pop. 1990 to Now | 73.2% | 113.6% | 30.8% |
| space4 | | | |
| Population Density | 2,577.6 | 1,668.4 | 93.4 |
| Land Area | 21.6 | 98.0 | 3,531,905.4 |
| Water Area | 0.0 | 0.7 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | DeSoto, TX | Clarksville, TN | United States |
| Age 0 to 4 | 5.5% | 8.9% | 5.9% |
| Age 5 to 9 | 6.5% | 7.7% | 6.1% |
| Age 10 to 14 | 7.2% | 7.1% | 6.6% |
| Age 15 to 17 | 5.1% | 3.7% | 3.9% |
| Age 18 to 20 | 4.3% | 4.4% | 4.0% |
| Age 21 to 24 | 3.8% | 7.2% | 5.2% |
| Age 25 to 34 | 11.5% | 20.3% | 13.8% |
| Age 35 to 44 | 13.2% | 13.8% | 12.9% |
| Age 45 to 54 | 17.2% | 9.6% | 12.6% |
| Age 55 to 59 | 6.9% | 4.3% | 6.7% |
| Age 60 to 64 | 4.9% | 4.6% | 6.3% |
| Age 65 to 74 | 9.2% | 5.3% | 9.6% |
| Age 75 to 84 | 3.4% | 2.2% | 4.5% |
| Age 85 and over | 1.2% | 0.8% | 1.9% |
| space1 | | | |
| Race | | | |
| | DeSoto, TX | Clarksville, TN | United States |
| White | 10.7% | 56.7% | 59.4% |
| Black | 66.8% | 21.8% | 12.2% |
| Asian | 0.7% | 2.6% | 5.6% |
| Native American | 0.1% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.3% | 0.2% |
| Other | 0.7% | 0.7% | 0.4% |
| Two or More Races | 3.2% | 5.9% | 3.2% |
| Hispanic | 17.9% | 11.7% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | DeSoto, TX | Clarksville, TN | United States |
| Married Population | 47.2% | 52.4% | 49.8% |
| Currently Married | 44.6% | 50.3% | 48.0% |
| Married but Separated | 2.7% | 2.1% | 1.8% |
| Single Population | 52.8% | 47.6% | 50.2% |
| Never Married | 35.8% | 30.2% | 33.8% |
| Divorced | 11.5% | 13.6% | 10.8% |
| Widowed | 5.5% | 3.9% | 5.6% |
| space5 | | | |
| Household Size | 2.78 | 2.69 | 2.60 |
| Households | 19,856 | 59,481 | 124,010,992 |
| Family Households | 13,595 | 41,036 | 80,755,759 |
| Married couple, w/children | 32.3% | 35.3% | 30.5% |
| Married couple, no children | 36.4% | 35.2% | 42.9% |
| Non Family Households | 6,261 | 18,445 | 43,255,233 |
| Single householder, w/children | 18.6% | 20.3% | 15.8% |
| Single householder, no children | 12.8% | 9.3% | 10.8% |