| | Independence, KY | Columbia, SC | United States |
| Population | 28,256 | 137,276 | 329,725,481 |
| Female Population | 49.1% | 50.0% | 50.5% |
| Male Population | 50.9% | 50.0% | 49.5% |
| Median Age | 34 | 28.2 | 38.4 |
| space3 | | | |
| Population - 2010 | 24,885 | 130,909 | 309,327,143 |
| Population - 2000 | 14,982 | 116,278 | 285,036,114 |
| Population - 1990 | 10,444 | 98,052 | 251,960,433 |
| Pop. 2000 to Now | 92.9% | 13.6% | 15.6% |
| Pop. 1990 to Now | 176.7% | 34.8% | 30.8% |
| space4 | | | |
| Population Density | 1,609.3 | 1,009.4 | 93.4 |
| Land Area | 17.6 | 136.0 | 3,531,905.4 |
| Water Area | 0.2 | 2.8 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Independence, KY | Columbia, SC | United States |
| Age 0 to 4 | 7.4% | 5.3% | 5.9% |
| Age 5 to 9 | 7.2% | 4.1% | 6.1% |
| Age 10 to 14 | 8.8% | 4.8% | 6.6% |
| Age 15 to 17 | 4.2% | 3.2% | 3.9% |
| Age 18 to 20 | 3.2% | 14.6% | 4.0% |
| Age 21 to 24 | 4.5% | 11.9% | 5.2% |
| Age 25 to 34 | 16.3% | 17.0% | 13.8% |
| Age 35 to 44 | 14.9% | 10.3% | 12.9% |
| Age 45 to 54 | 14.3% | 10.0% | 12.6% |
| Age 55 to 59 | 5.7% | 4.3% | 6.7% |
| Age 60 to 64 | 3.8% | 4.1% | 6.3% |
| Age 65 to 74 | 6.7% | 6.4% | 9.6% |
| Age 75 to 84 | 2.5% | 2.9% | 4.5% |
| Age 85 and over | 0.3% | 1.0% | 1.9% |
| space1 | | | |
| Race | | | |
| | Independence, KY | Columbia, SC | United States |
| White | 92.7% | 48.0% | 59.4% |
| Black | 2.7% | 40.3% | 12.2% |
| Asian | 1.1% | 2.6% | 5.6% |
| Native American | 0.1% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.2% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 2.2% | 2.8% | 3.2% |
| Hispanic | 1.2% | 5.6% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Independence, KY | Columbia, SC | United States |
| Married Population | 57.7% | 31.9% | 49.8% |
| Currently Married | 55.7% | 29.6% | 48.0% |
| Married but Separated | 2.0% | 2.3% | 1.8% |
| Single Population | 42.3% | 68.1% | 50.2% |
| Never Married | 28.5% | 55.7% | 33.8% |
| Divorced | 10.5% | 8.4% | 10.8% |
| Widowed | 3.3% | 4.0% | 5.6% |
| space5 | | | |
| Household Size | 2.89 | 2.19 | 2.60 |
| Households | 9,761 | 50,372 | 124,010,992 |
| Family Households | 7,330 | 24,276 | 80,755,759 |
| Married couple, w/children | 41.9% | 25.6% | 30.5% |
| Married couple, no children | 35.0% | 37.4% | 42.9% |
| Non Family Households | 2,431 | 26,096 | 43,255,233 |
| Single householder, w/children | 11.5% | 25.2% | 15.8% |
| Single householder, no children | 11.5% | 11.8% | 10.8% |