| | Pocomoke City, MD | Salisbury, MD | United States |
| Population | 4,276 | 32,583 | 329,725,481 |
| Female Population | 54.8% | 54.0% | 50.5% |
| Male Population | 45.2% | 46.1% | 49.5% |
| Median Age | 39.6 | 30.1 | 38.4 |
| space3 | | | |
| Population - 2010 | 4,182 | 30,386 | 309,327,143 |
| Population - 2000 | 4,098 | 23,743 | 285,036,114 |
| Population - 1990 | 3,922 | 20,592 | 251,960,433 |
| Pop. 2000 to Now | -0.1% | 39.1% | 15.6% |
| Pop. 1990 to Now | 4.4% | 60.3% | 30.8% |
| space4 | | | |
| Population Density | 1,142.4 | 2,378.2 | 93.4 |
| Land Area | 3.7 | 13.7 | 3,531,905.4 |
| Water Area | 0.2 | 0.5 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Pocomoke City, MD | Salisbury, MD | United States |
| Age 0 to 4 | 7.9% | 6.6% | 5.9% |
| Age 5 to 9 | 4.7% | 6.8% | 6.1% |
| Age 10 to 14 | 7.3% | 5.9% | 6.6% |
| Age 15 to 17 | 5.0% | 2.9% | 3.9% |
| Age 18 to 20 | 4.1% | 9.5% | 4.0% |
| Age 21 to 24 | 5.1% | 10.4% | 5.2% |
| Age 25 to 34 | 13.1% | 15.5% | 13.8% |
| Age 35 to 44 | 9.7% | 10.5% | 12.9% |
| Age 45 to 54 | 10.7% | 8.4% | 12.6% |
| Age 55 to 59 | 6.7% | 5.7% | 6.7% |
| Age 60 to 64 | 8.6% | 5.2% | 6.3% |
| Age 65 to 74 | 7.0% | 6.9% | 9.6% |
| Age 75 to 84 | 7.9% | 3.6% | 4.5% |
| Age 85 and over | 2.4% | 2.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Pocomoke City, MD | Salisbury, MD | United States |
| White | 43.9% | 46.9% | 59.4% |
| Black | 45.3% | 39.3% | 12.2% |
| Asian | 1.2% | 4.4% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.2% | 0.4% |
| Two or More Races | 4.4% | 4.8% | 3.2% |
| Hispanic | 5.2% | 4.3% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Pocomoke City, MD | Salisbury, MD | United States |
| Married Population | 40.3% | 28.7% | 49.8% |
| Currently Married | 38.2% | 27.2% | 48.0% |
| Married but Separated | 2.0% | 1.5% | 1.8% |
| Single Population | 59.7% | 71.3% | 50.2% |
| Never Married | 37.9% | 51.8% | 33.8% |
| Divorced | 11.3% | 13.1% | 10.8% |
| Widowed | 10.5% | 6.4% | 5.6% |
| space5 | | | |
| Household Size | 2.31 | 2.36 | 2.60 |
| Households | 1,817 | 13,171 | 124,010,992 |
| Family Households | 1,083 | 6,893 | 80,755,759 |
| Married couple, w/children | 28.0% | 19.6% | 30.5% |
| Married couple, no children | 27.3% | 28.3% | 42.9% |
| Non Family Households | 734 | 6,278 | 43,255,233 |
| Single householder, w/children | 24.7% | 33.9% | 15.8% |
| Single householder, no children | 19.9% | 18.2% | 10.8% |