| | Sanderson, TX | Del Rio, TX | United States |
| Population | 853 | 34,831 | 329,725,481 |
| Female Population | 53.0% | 49.1% | 50.5% |
| Male Population | 47.0% | 50.9% | 49.5% |
| Median Age | 54.2 | 33.2 | 38.4 |
| space3 | | | |
| Population - 2010 | 740 | 35,980 | 309,327,143 |
| Population - 2000 | 861 | 33,867 | 285,036,114 |
| Population - 1990 | 1,128 | 30,705 | 251,960,433 |
| Pop. 2000 to Now | -41.8% | 5.5% | 15.6% |
| Pop. 1990 to Now | -55.6% | 16.3% | 30.8% |
| space4 | | | |
| Population Density | 203.5 | 1,705.9 | 93.4 |
| Land Area | 4.2 | 20.4 | 3,531,905.4 |
| Water Area | 0.0 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Sanderson, TX | Del Rio, TX | United States |
| Age 0 to 4 | 2.6% | 8.0% | 5.9% |
| Age 5 to 9 | 6.3% | 7.2% | 6.1% |
| Age 10 to 14 | 3.5% | 9.4% | 6.6% |
| Age 15 to 17 | 3.8% | 5.0% | 3.9% |
| Age 18 to 20 | 1.5% | 4.2% | 4.0% |
| Age 21 to 24 | 0.7% | 5.9% | 5.2% |
| Age 25 to 34 | 8.9% | 13.4% | 13.8% |
| Age 35 to 44 | 8.8% | 12.9% | 12.9% |
| Age 45 to 54 | 15.8% | 10.4% | 12.6% |
| Age 55 to 59 | 5.0% | 4.6% | 6.7% |
| Age 60 to 64 | 15.5% | 4.8% | 6.3% |
| Age 65 to 74 | 16.5% | 7.4% | 9.6% |
| Age 75 to 84 | 9.6% | 4.7% | 4.5% |
| Age 85 and over | 1.4% | 2.2% | 1.9% |
| space1 | | | |
| Race | | | |
| | Sanderson, TX | Del Rio, TX | United States |
| White | 36.6% | 10.3% | 59.4% |
| Black | 1.6% | 0.9% | 12.2% |
| Asian | 0.0% | 0.5% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.2% | 0.4% |
| Two or More Races | 3.0% | 1.0% | 3.2% |
| Hispanic | 58.7% | 87.0% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Sanderson, TX | Del Rio, TX | United States |
| Married Population | 55.6% | 52.4% | 49.8% |
| Currently Married | 47.0% | 49.4% | 48.0% |
| Married but Separated | 8.6% | 3.0% | 1.8% |
| Single Population | 44.4% | 47.6% | 50.2% |
| Never Married | 22.6% | 29.4% | 33.8% |
| Divorced | 5.1% | 9.9% | 10.8% |
| Widowed | 16.7% | 8.2% | 5.6% |
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| Household Size | 2.58 | 2.84 | 2.60 |
| Households | 330 | 11,857 | 124,010,992 |
| Family Households | 213 | 8,627 | 80,755,759 |
| Married couple, w/children | 18.3% | 36.4% | 30.5% |
| Married couple, no children | 49.3% | 29.6% | 42.9% |
| Non Family Households | 117 | 3,230 | 43,255,233 |
| Single householder, w/children | 9.9% | 24.1% | 15.8% |
| Single householder, no children | 22.5% | 9.9% | 10.8% |