| | Scottsbluff, NE | Cherokee, IA | United States |
| Population | 14,511 | 5,141 | 329,725,481 |
| Female Population | 53.6% | 49.8% | 50.5% |
| Male Population | 46.4% | 50.2% | 49.5% |
| Median Age | 35 | 44.3 | 38.4 |
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| Population - 2010 | 15,081 | 5,272 | 309,327,143 |
| Population - 2000 | 14,732 | 5,369 | 285,036,114 |
| Population - 1990 | 13,711 | 6,026 | 251,960,433 |
| Pop. 2000 to Now | -2.4% | -9.8% | 15.6% |
| Pop. 1990 to Now | 4.8% | -19.7% | 30.8% |
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| Population Density | 2,207.7 | 786.0 | 93.4 |
| Land Area | 6.6 | 6.5 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Scottsbluff, NE | Cherokee, IA | United States |
| Age 0 to 4 | 6.9% | 5.2% | 5.9% |
| Age 5 to 9 | 9.1% | 4.7% | 6.1% |
| Age 10 to 14 | 7.5% | 9.6% | 6.6% |
| Age 15 to 17 | 4.1% | 5.1% | 3.9% |
| Age 18 to 20 | 4.2% | 3.0% | 4.0% |
| Age 21 to 24 | 4.7% | 2.5% | 5.2% |
| Age 25 to 34 | 13.7% | 8.4% | 13.8% |
| Age 35 to 44 | 10.9% | 13.2% | 12.9% |
| Age 45 to 54 | 9.4% | 13.3% | 12.6% |
| Age 55 to 59 | 5.0% | 5.8% | 6.7% |
| Age 60 to 64 | 5.3% | 6.8% | 6.3% |
| Age 65 to 74 | 10.8% | 11.0% | 9.6% |
| Age 75 to 84 | 4.2% | 7.5% | 4.5% |
| Age 85 and over | 4.4% | 3.9% | 1.9% |
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| Race | | | |
| | Scottsbluff, NE | Cherokee, IA | United States |
| White | 64.6% | 95.6% | 59.4% |
| Black | 0.9% | 0.9% | 12.2% |
| Asian | 0.8% | 0.9% | 5.6% |
| Native American | 3.5% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 2.0% | 2.5% | 3.2% |
| Hispanic | 28.2% | 0.2% | 18.4% |
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| Marriage & Family | | | |
| | Scottsbluff, NE | Cherokee, IA | United States |
| Married Population | 46.3% | 45.4% | 49.8% |
| Currently Married | 44.7% | 43.0% | 48.0% |
| Married but Separated | 1.6% | 2.4% | 1.8% |
| Single Population | 53.7% | 54.6% | 50.2% |
| Never Married | 31.0% | 33.9% | 33.8% |
| Divorced | 13.7% | 10.7% | 10.8% |
| Widowed | 9.1% | 10.1% | 5.6% |
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| Household Size | 2.39 | 2.09 | 2.60 |
| Households | 5,909 | 2,268 | 124,010,992 |
| Family Households | 3,339 | 1,078 | 80,755,759 |
| Married couple, w/children | 30.9% | 37.8% | 30.5% |
| Married couple, no children | 36.5% | 43.0% | 42.9% |
| Non Family Households | 2,570 | 1,190 | 43,255,233 |
| Single householder, w/children | 25.3% | 18.0% | 15.8% |
| Single householder, no children | 7.2% | 1.1% | 10.8% |