| | Bluefield, VA | Wytheville, VA | United States |
| Population | 5,079 | 8,260 | 329,725,481 |
| Female Population | 51.6% | 48.4% | 50.5% |
| Male Population | 48.4% | 51.6% | 49.5% |
| Median Age | 45.5 | 46.8 | 38.4 |
| space3 | | | |
| Population - 2010 | 5,397 | 8,207 | 309,327,143 |
| Population - 2000 | 5,078 | 7,804 | 285,036,114 |
| Population - 1990 | 5,363 | 8,038 | 251,960,433 |
| Pop. 2000 to Now | -5.2% | 1.0% | 15.6% |
| Pop. 1990 to Now | -10.2% | -2.0% | 30.8% |
| space4 | | | |
| Population Density | 534.9 | 570.1 | 93.4 |
| Land Area | 9.5 | 14.5 | 3,531,905.4 |
| Water Area | 0.0 | 0.1 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Bluefield, VA | Wytheville, VA | United States |
| Age 0 to 4 | 6.1% | 4.4% | 5.9% |
| Age 5 to 9 | 6.2% | 6.1% | 6.1% |
| Age 10 to 14 | 3.1% | 6.1% | 6.6% |
| Age 15 to 17 | 3.4% | 3.9% | 3.9% |
| Age 18 to 20 | 4.3% | 2.5% | 4.0% |
| Age 21 to 24 | 8.1% | 4.5% | 5.2% |
| Age 25 to 34 | 9.8% | 9.5% | 13.8% |
| Age 35 to 44 | 7.8% | 10.7% | 12.9% |
| Age 45 to 54 | 15.3% | 16.0% | 12.6% |
| Age 55 to 59 | 6.3% | 5.6% | 6.7% |
| Age 60 to 64 | 7.6% | 5.3% | 6.3% |
| Age 65 to 74 | 8.7% | 13.9% | 9.6% |
| Age 75 to 84 | 9.5% | 7.1% | 4.5% |
| Age 85 and over | 3.8% | 4.4% | 1.9% |
| space1 | | | |
| Race | | | |
| | Bluefield, VA | Wytheville, VA | United States |
| White | 89.7% | 91.3% | 59.4% |
| Black | 5.6% | 3.3% | 12.2% |
| Asian | 0.8% | 2.3% | 5.6% |
| Native American | 0.5% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.3% | 0.2% |
| Other | 0.0% | 0.0% | 0.4% |
| Two or More Races | 0.7% | 1.4% | 3.2% |
| Hispanic | 2.7% | 1.4% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Bluefield, VA | Wytheville, VA | United States |
| Married Population | 50.7% | 47.9% | 49.8% |
| Currently Married | 49.7% | 43.2% | 48.0% |
| Married but Separated | 1.0% | 4.7% | 1.8% |
| Single Population | 49.3% | 52.1% | 50.2% |
| Never Married | 32.4% | 28.4% | 33.8% |
| Divorced | 10.9% | 14.3% | 10.8% |
| Widowed | 6.0% | 9.5% | 5.6% |
| space5 | | | |
| Household Size | 2.28 | 2.06 | 2.60 |
| Households | 2,100 | 3,926 | 124,010,992 |
| Family Households | 1,499 | 1,986 | 80,755,759 |
| Married couple, w/children | 19.5% | 25.4% | 30.5% |
| Married couple, no children | 50.0% | 46.5% | 42.9% |
| Non Family Households | 601 | 1,940 | 43,255,233 |
| Single householder, w/children | 23.0% | 21.6% | 15.8% |
| Single householder, no children | 7.4% | 6.5% | 10.8% |