| | Florissant, MO | Independence, MO | United States |
| Population | 52,382 | 122,230 | 329,725,481 |
| Female Population | 52.2% | 51.6% | 50.5% |
| Male Population | 47.9% | 48.4% | 49.5% |
| Median Age | 37.5 | 39.5 | 38.4 |
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| Population - 2010 | 52,237 | 116,904 | 309,327,143 |
| Population - 2000 | 50,497 | 113,288 | 285,036,114 |
| Population - 1990 | 51,206 | 112,301 | 251,960,433 |
| Pop. 2000 to Now | 0.6% | 3.1% | 15.6% |
| Pop. 1990 to Now | -0.8% | 4.0% | 30.8% |
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| Population Density | 4,157.3 | 1,570.4 | 93.4 |
| Land Area | 12.6 | 77.8 | 3,531,905.4 |
| Water Area | 0.3 | 0.4 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Florissant, MO | Independence, MO | United States |
| Age 0 to 4 | 6.1% | 6.2% | 5.9% |
| Age 5 to 9 | 6.0% | 6.1% | 6.1% |
| Age 10 to 14 | 7.6% | 6.6% | 6.6% |
| Age 15 to 17 | 4.2% | 4.0% | 3.9% |
| Age 18 to 20 | 3.9% | 3.3% | 4.0% |
| Age 21 to 24 | 4.8% | 4.6% | 5.2% |
| Age 25 to 34 | 13.8% | 13.5% | 13.8% |
| Age 35 to 44 | 13.2% | 12.2% | 12.9% |
| Age 45 to 54 | 11.4% | 11.7% | 12.6% |
| Age 55 to 59 | 7.6% | 7.1% | 6.7% |
| Age 60 to 64 | 7.3% | 6.7% | 6.3% |
| Age 65 to 74 | 8.0% | 9.9% | 9.6% |
| Age 75 to 84 | 4.2% | 5.2% | 4.5% |
| Age 85 and over | 2.0% | 2.7% | 1.9% |
| space1 | | | |
| Race | | | |
| | Florissant, MO | Independence, MO | United States |
| White | 50.7% | 74.2% | 59.4% |
| Black | 38.6% | 9.6% | 12.2% |
| Asian | 1.1% | 1.1% | 5.6% |
| Native American | 0.0% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 1.3% | 0.2% |
| Other | 1.3% | 0.9% | 0.4% |
| Two or More Races | 5.8% | 3.3% | 3.2% |
| Hispanic | 2.4% | 9.5% | 18.4% |
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| Marriage & Family | | | |
| | Florissant, MO | Independence, MO | United States |
| Married Population | 43.5% | 45.8% | 49.8% |
| Currently Married | 41.2% | 44.0% | 48.0% |
| Married but Separated | 2.3% | 1.9% | 1.8% |
| Single Population | 56.5% | 54.2% | 50.2% |
| Never Married | 37.2% | 31.4% | 33.8% |
| Divorced | 12.5% | 15.4% | 10.8% |
| Widowed | 6.8% | 7.4% | 5.6% |
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| Household Size | 2.52 | 2.41 | 2.60 |
| Households | 20,468 | 50,293 | 124,010,992 |
| Family Households | 12,918 | 30,108 | 80,755,759 |
| Married couple, w/children | 25.8% | 25.2% | 30.5% |
| Married couple, no children | 37.0% | 43.0% | 42.9% |
| Non Family Households | 7,550 | 20,185 | 43,255,233 |
| Single householder, w/children | 20.6% | 19.8% | 15.8% |
| Single householder, no children | 16.6% | 12.0% | 10.8% |