| | Henderson, KY | Evansville, IN | United States |
| Population | 28,201 | 117,184 | 329,725,481 |
| Female Population | 53.0% | 51.3% | 50.5% |
| Male Population | 47.0% | 48.7% | 49.5% |
| Median Age | 40 | 38.2 | 38.4 |
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| Population - 2010 | 28,952 | 120,092 | 309,327,143 |
| Population - 2000 | 27,373 | 121,582 | 285,036,114 |
| Population - 1990 | 25,945 | 126,272 | 251,960,433 |
| Pop. 2000 to Now | 2.2% | -2.6% | 15.6% |
| Pop. 1990 to Now | 7.8% | -6.2% | 30.8% |
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| Population Density | 1,749.6 | 2,476.5 | 93.4 |
| Land Area | 16.1 | 47.3 | 3,531,905.4 |
| Water Area | 2.3 | 0.5 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Henderson, KY | Evansville, IN | United States |
| Age 0 to 4 | 6.3% | 6.3% | 5.9% |
| Age 5 to 9 | 5.1% | 5.7% | 6.1% |
| Age 10 to 14 | 7.1% | 6.0% | 6.6% |
| Age 15 to 17 | 4.2% | 3.1% | 3.9% |
| Age 18 to 20 | 3.3% | 3.5% | 4.0% |
| Age 21 to 24 | 4.5% | 6.4% | 5.2% |
| Age 25 to 34 | 13.8% | 14.9% | 13.8% |
| Age 35 to 44 | 12.4% | 12.3% | 12.9% |
| Age 45 to 54 | 12.3% | 11.9% | 12.6% |
| Age 55 to 59 | 7.8% | 6.9% | 6.7% |
| Age 60 to 64 | 5.9% | 6.6% | 6.3% |
| Age 65 to 74 | 10.3% | 9.5% | 9.6% |
| Age 75 to 84 | 5.1% | 4.6% | 4.5% |
| Age 85 and over | 2.0% | 2.3% | 1.9% |
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| Race | | | |
| | Henderson, KY | Evansville, IN | United States |
| White | 80.2% | 77.8% | 59.4% |
| Black | 10.1% | 13.5% | 12.2% |
| Asian | 0.6% | 1.0% | 5.6% |
| Native American | 0.3% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.3% | 0.2% |
| Other | 0.3% | 0.4% | 0.4% |
| Two or More Races | 4.9% | 3.6% | 3.2% |
| Hispanic | 3.7% | 3.3% | 18.4% |
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| Marriage & Family | | | |
| | Henderson, KY | Evansville, IN | United States |
| Married Population | 47.9% | 40.4% | 49.8% |
| Currently Married | 45.0% | 39.1% | 48.0% |
| Married but Separated | 2.9% | 1.3% | 1.8% |
| Single Population | 52.1% | 59.6% | 50.2% |
| Never Married | 28.5% | 35.1% | 33.8% |
| Divorced | 14.8% | 17.8% | 10.8% |
| Widowed | 8.7% | 6.7% | 5.6% |
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| Household Size | 2.26 | 2.17 | 2.60 |
| Households | 11,894 | 52,114 | 124,010,992 |
| Family Households | 7,008 | 28,424 | 80,755,759 |
| Married couple, w/children | 27.6% | 21.0% | 30.5% |
| Married couple, no children | 40.8% | 40.0% | 42.9% |
| Non Family Households | 4,886 | 23,690 | 43,255,233 |
| Single householder, w/children | 21.9% | 24.7% | 15.8% |
| Single householder, no children | 9.8% | 14.2% | 10.8% |