| | Indianapolis, IN | Owensboro, KY | United States |
| Population | 880,104 | 59,839 | 329,725,481 |
| Female Population | 51.5% | 51.8% | 50.5% |
| Male Population | 48.5% | 48.2% | 49.5% |
| Median Age | 34.3 | 37.6 | 38.4 |
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| Population - 2010 | 821,576 | 57,506 | 309,327,143 |
| Population - 2000 | 781,870 | 54,067 | 285,036,114 |
| Population - 1990 | 754,005 | 53,549 | 251,960,433 |
| Pop. 2000 to Now | 12.3% | 11.6% | 15.6% |
| Pop. 1990 to Now | 16.4% | 12.7% | 30.8% |
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| Population Density | 2,434.0 | 2,924.8 | 93.4 |
| Land Area | 361.6 | 20.5 | 3,531,905.4 |
| Water Area | 6.5 | 1.4 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Indianapolis, IN | Owensboro, KY | United States |
| Age 0 to 4 | 7.1% | 7.5% | 5.9% |
| Age 5 to 9 | 6.8% | 6.3% | 6.1% |
| Age 10 to 14 | 6.9% | 6.4% | 6.6% |
| Age 15 to 17 | 3.9% | 4.1% | 3.9% |
| Age 18 to 20 | 3.9% | 4.2% | 4.0% |
| Age 21 to 24 | 5.6% | 5.4% | 5.2% |
| Age 25 to 34 | 16.8% | 13.5% | 13.8% |
| Age 35 to 44 | 13.0% | 10.9% | 12.9% |
| Age 45 to 54 | 11.6% | 11.2% | 12.6% |
| Age 55 to 59 | 6.1% | 6.3% | 6.7% |
| Age 60 to 64 | 5.8% | 5.8% | 6.3% |
| Age 65 to 74 | 7.7% | 10.7% | 9.6% |
| Age 75 to 84 | 3.3% | 5.1% | 4.5% |
| Age 85 and over | 1.5% | 2.8% | 1.9% |
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| Race | | | |
| | Indianapolis, IN | Owensboro, KY | United States |
| White | 52.7% | 81.8% | 59.4% |
| Black | 28.5% | 6.8% | 12.2% |
| Asian | 3.8% | 2.7% | 5.6% |
| Native American | 0.1% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.5% | 0.6% | 0.4% |
| Two or More Races | 3.7% | 3.0% | 3.2% |
| Hispanic | 10.8% | 4.8% | 18.4% |
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| Marriage & Family | | | |
| | Indianapolis, IN | Owensboro, KY | United States |
| Married Population | 41.1% | 44.6% | 49.8% |
| Currently Married | 39.4% | 42.4% | 48.0% |
| Married but Separated | 1.7% | 2.2% | 1.8% |
| Single Population | 58.9% | 55.4% | 50.2% |
| Never Married | 41.8% | 30.7% | 33.8% |
| Divorced | 12.3% | 17.2% | 10.8% |
| Widowed | 4.8% | 7.6% | 5.6% |
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| Household Size | 2.46 | 2.30 | 2.60 |
| Households | 352,238 | 25,079 | 124,010,992 |
| Family Households | 193,246 | 14,905 | 80,755,759 |
| Married couple, w/children | 26.6% | 26.6% | 30.5% |
| Married couple, no children | 38.7% | 37.6% | 42.9% |
| Non Family Households | 158,992 | 10,174 | 43,255,233 |
| Single householder, w/children | 22.4% | 25.2% | 15.8% |
| Single householder, no children | 12.4% | 10.6% | 10.8% |