| | Mishicot, WI | Port Isabel, TX | United States |
| Population | 1,474 | 5,208 | 329,725,481 |
| Female Population | 52.8% | 50.5% | 50.5% |
| Male Population | 47.2% | 49.5% | 49.5% |
| Median Age | 47.7 | 37.9 | 38.4 |
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| Population - 2010 | 1,444 | 6,314 | 309,327,143 |
| Population - 2000 | 1,422 | 4,865 | 285,036,114 |
| Population - 1990 | 1,296 | 4,467 | 251,960,433 |
| Pop. 2000 to Now | -2.3% | 28.0% | 15.6% |
| Pop. 1990 to Now | 7.2% | 39.4% | 30.8% |
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| Population Density | 577.8 | 776.9 | 93.4 |
| Land Area | 2.6 | 6.7 | 3,531,905.4 |
| Water Area | 0.0 | 7.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Mishicot, WI | Port Isabel, TX | United States |
| Age 0 to 4 | 3.9% | 6.4% | 5.9% |
| Age 5 to 9 | 5.0% | 8.2% | 6.1% |
| Age 10 to 14 | 8.0% | 10.0% | 6.6% |
| Age 15 to 17 | 1.8% | 3.4% | 3.9% |
| Age 18 to 20 | 3.1% | 2.0% | 4.0% |
| Age 21 to 24 | 2.6% | 2.3% | 5.2% |
| Age 25 to 34 | 9.6% | 13.0% | 13.8% |
| Age 35 to 44 | 14.1% | 13.0% | 12.9% |
| Age 45 to 54 | 15.9% | 8.9% | 12.6% |
| Age 55 to 59 | 6.9% | 7.0% | 6.7% |
| Age 60 to 64 | 5.4% | 7.5% | 6.3% |
| Age 65 to 74 | 10.5% | 10.0% | 9.6% |
| Age 75 to 84 | 11.3% | 6.5% | 4.5% |
| Age 85 and over | 2.0% | 1.8% | 1.9% |
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| Race | | | |
| | Mishicot, WI | Port Isabel, TX | United States |
| White | 97.8% | 14.7% | 59.4% |
| Black | 0.0% | 0.0% | 12.2% |
| Asian | 0.7% | 1.4% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 1.7% | 0.4% |
| Two or More Races | 0.0% | 0.3% | 3.2% |
| Hispanic | 1.5% | 82.0% | 18.4% |
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| Marriage & Family | | | |
| | Mishicot, WI | Port Isabel, TX | United States |
| Married Population | 59.0% | 58.3% | 49.8% |
| Currently Married | 58.0% | 53.9% | 48.0% |
| Married but Separated | 1.1% | 4.4% | 1.8% |
| Single Population | 41.0% | 41.7% | 50.2% |
| Never Married | 18.4% | 25.7% | 33.8% |
| Divorced | 10.0% | 9.4% | 10.8% |
| Widowed | 12.5% | 6.7% | 5.6% |
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| Household Size | 2.18 | 2.87 | 2.60 |
| Households | 675 | 1,817 | 124,010,992 |
| Family Households | 418 | 1,254 | 80,755,759 |
| Married couple, w/children | 24.2% | 28.4% | 30.5% |
| Married couple, no children | 53.1% | 35.9% | 42.9% |
| Non Family Households | 257 | 563 | 43,255,233 |
| Single householder, w/children | 15.3% | 25.4% | 15.8% |
| Single householder, no children | 7.4% | 10.4% | 10.8% |