| | Osborne, KS | Marquette, KS | United States |
| Population | 1,554 | 679 | 329,725,481 |
| Female Population | 51.8% | 51.8% | 50.5% |
| Male Population | 48.2% | 48.2% | 49.5% |
| Median Age | 43.3 | 52.1 | 38.4 |
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| Population - 2010 | 1,432 | 648 | 309,327,143 |
| Population - 2000 | 1,607 | 542 | 285,036,114 |
| Population - 1990 | 1,778 | 593 | 251,960,433 |
| Pop. 2000 to Now | -20.4% | 9.8% | 15.6% |
| Pop. 1990 to Now | -28.0% | 0.3% | 30.8% |
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| Population Density | 986.0 | 1,408.7 | 93.4 |
| Land Area | 1.6 | 0.5 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Osborne, KS | Marquette, KS | United States |
| Age 0 to 4 | 5.5% | 4.0% | 5.9% |
| Age 5 to 9 | 5.9% | 5.0% | 6.1% |
| Age 10 to 14 | 4.4% | 4.0% | 6.6% |
| Age 15 to 17 | 4.8% | 2.1% | 3.9% |
| Age 18 to 20 | 4.8% | 2.7% | 4.0% |
| Age 21 to 24 | 5.9% | 5.4% | 5.2% |
| Age 25 to 34 | 9.4% | 5.3% | 13.8% |
| Age 35 to 44 | 11.7% | 11.0% | 12.9% |
| Age 45 to 54 | 8.8% | 15.5% | 12.6% |
| Age 55 to 59 | 10.4% | 6.6% | 6.7% |
| Age 60 to 64 | 5.1% | 4.7% | 6.3% |
| Age 65 to 74 | 11.1% | 27.1% | 9.6% |
| Age 75 to 84 | 5.3% | 4.1% | 4.5% |
| Age 85 and over | 6.9% | 2.5% | 1.9% |
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| Race | | | |
| | Osborne, KS | Marquette, KS | United States |
| White | 90.2% | 92.0% | 59.4% |
| Black | 1.0% | 0.0% | 12.2% |
| Asian | 0.0% | 0.0% | 5.6% |
| Native American | 0.4% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.5% | 0.0% | 0.4% |
| Two or More Races | 5.2% | 1.8% | 3.2% |
| Hispanic | 2.8% | 6.2% | 18.4% |
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| Marriage & Family | | | |
| | Osborne, KS | Marquette, KS | United States |
| Married Population | 47.6% | 54.3% | 49.8% |
| Currently Married | 46.1% | 54.0% | 48.0% |
| Married but Separated | 1.5% | 0.3% | 1.8% |
| Single Population | 52.4% | 45.7% | 50.2% |
| Never Married | 23.4% | 21.7% | 33.8% |
| Divorced | 18.3% | 17.6% | 10.8% |
| Widowed | 10.6% | 6.4% | 5.6% |
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| Household Size | 2.14 | 2.20 | 2.60 |
| Households | 704 | 295 | 124,010,992 |
| Family Households | 405 | 181 | 80,755,759 |
| Married couple, w/children | 29.9% | 15.5% | 30.5% |
| Married couple, no children | 37.0% | 55.2% | 42.9% |
| Non Family Households | 299 | 114 | 43,255,233 |
| Single householder, w/children | 23.2% | 16.6% | 15.8% |
| Single householder, no children | 9.9% | 12.7% | 10.8% |