| | Otis, CO | Holyoke, CO | United States |
| Population | 526 | 2,416 | 329,725,481 |
| Female Population | 51.0% | 49.2% | 50.5% |
| Male Population | 49.1% | 50.8% | 49.5% |
| Median Age | 32.8 | 37.5 | 38.4 |
| space3 | | | |
| Population - 2010 | 473 | 2,331 | 309,327,143 |
| Population - 2000 | 534 | 2,261 | 285,036,114 |
| Population - 1990 | 451 | 1,931 | 251,960,433 |
| Pop. 2000 to Now | -9.4% | -1.0% | 15.6% |
| Pop. 1990 to Now | 7.3% | 16.0% | 30.8% |
| space4 | | | |
| Population Density | 1,273.6 | 1,021.1 | 93.4 |
| Land Area | 0.4 | 2.4 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Otis, CO | Holyoke, CO | United States |
| Age 0 to 4 | 11.0% | 13.0% | 5.9% |
| Age 5 to 9 | 13.1% | 6.7% | 6.1% |
| Age 10 to 14 | 5.7% | 7.0% | 6.6% |
| Age 15 to 17 | 1.7% | 3.4% | 3.9% |
| Age 18 to 20 | 1.9% | 4.1% | 4.0% |
| Age 21 to 24 | 1.5% | 2.8% | 5.2% |
| Age 25 to 34 | 25.5% | 8.2% | 13.8% |
| Age 35 to 44 | 4.6% | 15.8% | 12.9% |
| Age 45 to 54 | 10.1% | 12.5% | 12.6% |
| Age 55 to 59 | 5.7% | 3.5% | 6.7% |
| Age 60 to 64 | 4.0% | 7.0% | 6.3% |
| Age 65 to 74 | 8.4% | 4.9% | 9.6% |
| Age 75 to 84 | 4.4% | 5.8% | 4.5% |
| Age 85 and over | 2.5% | 5.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | Otis, CO | Holyoke, CO | United States |
| White | 90.3% | 52.3% | 59.4% |
| Black | 0.8% | 0.0% | 12.2% |
| Asian | 0.0% | 0.4% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.2% | 0.0% | 0.2% |
| Other | 0.0% | 0.2% | 0.4% |
| Two or More Races | 1.9% | 0.5% | 3.2% |
| Hispanic | 6.8% | 46.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Otis, CO | Holyoke, CO | United States |
| Married Population | 69.6% | 58.5% | 49.8% |
| Currently Married | 69.6% | 55.4% | 48.0% |
| Married but Separated | 0.0% | 3.0% | 1.8% |
| Single Population | 30.4% | 41.5% | 50.2% |
| Never Married | 8.7% | 19.7% | 33.8% |
| Divorced | 17.1% | 13.0% | 10.8% |
| Widowed | 4.6% | 8.8% | 5.6% |
| space5 | | | |
| Household Size | 2.50 | 2.60 | 2.60 |
| Households | 210 | 913 | 124,010,992 |
| Family Households | 161 | 646 | 80,755,759 |
| Married couple, w/children | 33.5% | 44.6% | 30.5% |
| Married couple, no children | 36.6% | 29.6% | 42.9% |
| Non Family Households | 49 | 267 | 43,255,233 |
| Single householder, w/children | 26.1% | 5.4% | 15.8% |
| Single householder, no children | 3.7% | 20.4% | 10.8% |