| | Otis, MA | Barnstable Town, MA | United States |
| Population | 1,460 | 48,556 | 329,725,481 |
| Female Population | 49.0% | 51.4% | 50.5% |
| Male Population | 51.0% | 48.6% | 49.5% |
| Median Age | 53 | 47.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,611 | 45,157 | 309,327,143 |
| Population - 2000 | 1,365 | 47,925 | 285,036,114 |
| Population - 1990 | 1,073 | 41,032 | 251,960,433 |
| Pop. 2000 to Now | 12.2% | -7.1% | 15.6% |
| Pop. 1990 to Now | 42.7% | 8.5% | 30.8% |
| space4 | | | |
| Population Density | 41.1 | 810.2 | 93.4 |
| Land Area | 35.5 | 59.9 | 3,531,905.4 |
| Water Area | 2.5 | 16.5 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Otis, MA | Barnstable Town, MA | United States |
| Age 0 to 4 | 2.5% | 4.3% | 5.9% |
| Age 5 to 9 | 3.2% | 4.7% | 6.1% |
| Age 10 to 14 | 2.2% | 6.2% | 6.6% |
| Age 15 to 17 | 4.3% | 2.7% | 3.9% |
| Age 18 to 20 | 0.5% | 3.1% | 4.0% |
| Age 21 to 24 | 1.4% | 3.8% | 5.2% |
| Age 25 to 34 | 16.2% | 11.3% | 13.8% |
| Age 35 to 44 | 7.9% | 11.2% | 12.9% |
| Age 45 to 54 | 17.5% | 12.8% | 12.6% |
| Age 55 to 59 | 10.9% | 8.1% | 6.7% |
| Age 60 to 64 | 8.7% | 8.5% | 6.3% |
| Age 65 to 74 | 11.6% | 14.0% | 9.6% |
| Age 75 to 84 | 10.5% | 6.3% | 4.5% |
| Age 85 and over | 2.3% | 3.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Otis, MA | Barnstable Town, MA | United States |
| White | 96.3% | 79.1% | 59.4% |
| Black | 0.0% | 5.5% | 12.2% |
| Asian | 0.0% | 0.9% | 5.6% |
| Native American | 0.3% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 2.2% | 0.4% |
| Two or More Races | 1.3% | 5.4% | 3.2% |
| Hispanic | 2.1% | 6.8% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Otis, MA | Barnstable Town, MA | United States |
| Married Population | 56.8% | 53.5% | 49.8% |
| Currently Married | 53.8% | 52.0% | 48.0% |
| Married but Separated | 3.0% | 1.5% | 1.8% |
| Single Population | 43.2% | 46.5% | 50.2% |
| Never Married | 27.6% | 28.9% | 33.8% |
| Divorced | 9.3% | 12.4% | 10.8% |
| Widowed | 6.3% | 5.2% | 5.6% |
| space5 | | | |
| Household Size | 2.10 | 2.43 | 2.60 |
| Households | 694 | 19,748 | 124,010,992 |
| Family Households | 381 | 12,764 | 80,755,759 |
| Married couple, w/children | 27.8% | 24.6% | 30.5% |
| Married couple, no children | 64.0% | 53.5% | 42.9% |
| Non Family Households | 313 | 6,984 | 43,255,233 |
| Single householder, w/children | 4.2% | 12.6% | 15.8% |
| Single householder, no children | 3.9% | 9.3% | 10.8% |