| | Pendleton, OR | La Grande, OR | United States |
| Population | 16,861 | 13,212 | 329,725,481 |
| Female Population | 45.6% | 52.4% | 50.5% |
| Male Population | 54.4% | 47.6% | 49.5% |
| Median Age | 36.9 | 34 | 38.4 |
| space3 | | | |
| Population - 2010 | 16,656 | 13,088 | 309,327,143 |
| Population - 2000 | 16,354 | 12,327 | 285,036,114 |
| Population - 1990 | 15,126 | 11,766 | 251,960,433 |
| Pop. 2000 to Now | 1.5% | 8.7% | 15.6% |
| Pop. 1990 to Now | 9.7% | 13.9% | 30.8% |
| space4 | | | |
| Population Density | 1,438.3 | 2,903.1 | 93.4 |
| Land Area | 11.7 | 4.6 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Pendleton, OR | La Grande, OR | United States |
| Age 0 to 4 | 7.5% | 5.9% | 5.9% |
| Age 5 to 9 | 6.1% | 8.6% | 6.1% |
| Age 10 to 14 | 7.0% | 4.6% | 6.6% |
| Age 15 to 17 | 4.1% | 4.1% | 3.9% |
| Age 18 to 20 | 4.5% | 7.5% | 4.0% |
| Age 21 to 24 | 3.7% | 6.9% | 5.2% |
| Age 25 to 34 | 14.1% | 14.0% | 13.8% |
| Age 35 to 44 | 14.0% | 10.3% | 12.9% |
| Age 45 to 54 | 11.0% | 8.2% | 12.6% |
| Age 55 to 59 | 5.8% | 5.8% | 6.7% |
| Age 60 to 64 | 5.5% | 6.4% | 6.3% |
| Age 65 to 74 | 10.4% | 10.0% | 9.6% |
| Age 75 to 84 | 3.6% | 5.7% | 4.5% |
| Age 85 and over | 2.6% | 2.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Pendleton, OR | La Grande, OR | United States |
| White | 78.4% | 85.4% | 59.4% |
| Black | 1.9% | 0.7% | 12.2% |
| Asian | 0.6% | 1.0% | 5.6% |
| Native American | 2.1% | 0.6% | 0.6% |
| Hawaiian, Pacific Islander | 0.1% | 2.5% | 0.2% |
| Other | 0.7% | 0.0% | 0.4% |
| Two or More Races | 4.2% | 3.2% | 3.2% |
| Hispanic | 12.0% | 6.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Pendleton, OR | La Grande, OR | United States |
| Married Population | 44.8% | 43.1% | 49.8% |
| Currently Married | 42.3% | 40.1% | 48.0% |
| Married but Separated | 2.6% | 2.9% | 1.8% |
| Single Population | 55.2% | 56.9% | 50.2% |
| Never Married | 33.7% | 37.1% | 33.8% |
| Divorced | 14.8% | 12.0% | 10.8% |
| Widowed | 6.7% | 7.8% | 5.6% |
| space5 | | | |
| Household Size | 2.57 | 2.43 | 2.60 |
| Households | 5,876 | 5,220 | 124,010,992 |
| Family Households | 3,555 | 3,154 | 80,755,759 |
| Married couple, w/children | 32.9% | 27.2% | 30.5% |
| Married couple, no children | 37.1% | 38.1% | 42.9% |
| Non Family Households | 2,321 | 2,066 | 43,255,233 |
| Single householder, w/children | 22.4% | 22.6% | 15.8% |
| Single householder, no children | 7.6% | 12.1% | 10.8% |