| | Pickens, MS | Central, SC | United States |
| Population | 1,281 | 5,229 | 329,725,481 |
| Female Population | 62.5% | 54.4% | 50.5% |
| Male Population | 37.6% | 45.6% | 49.5% |
| Median Age | 34.5 | 23.7 | 38.4 |
| space3 | | | |
| Population - 2010 | 1,156 | 5,199 | 309,327,143 |
| Population - 2000 | 1,325 | 3,522 | 285,036,114 |
| Population - 1990 | 1,285 | 2,438 | 251,960,433 |
| Pop. 2000 to Now | -26.3% | 54.8% | 15.6% |
| Pop. 1990 to Now | -24.1% | 123.6% | 30.8% |
| space4 | | | |
| Population Density | 1,003.1 | 1,890.5 | 93.4 |
| Land Area | 1.3 | 2.8 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Pickens, MS | Central, SC | United States |
| Age 0 to 4 | 6.2% | 9.0% | 5.9% |
| Age 5 to 9 | 13.0% | 2.1% | 6.1% |
| Age 10 to 14 | 5.1% | 3.5% | 6.6% |
| Age 15 to 17 | 5.9% | 1.9% | 3.9% |
| Age 18 to 20 | 3.6% | 23.2% | 4.0% |
| Age 21 to 24 | 5.3% | 12.1% | 5.2% |
| Age 25 to 34 | 14.3% | 14.2% | 13.8% |
| Age 35 to 44 | 5.2% | 7.5% | 12.9% |
| Age 45 to 54 | 11.4% | 11.0% | 12.6% |
| Age 55 to 59 | 5.2% | 3.3% | 6.7% |
| Age 60 to 64 | 5.2% | 2.6% | 6.3% |
| Age 65 to 74 | 12.8% | 5.6% | 9.6% |
| Age 75 to 84 | 6.4% | 2.7% | 4.5% |
| Age 85 and over | 0.5% | 1.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | Pickens, MS | Central, SC | United States |
| White | 2.6% | 59.2% | 59.4% |
| Black | 97.4% | 12.4% | 12.2% |
| Asian | 0.0% | 5.2% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.5% | 0.4% |
| Two or More Races | 0.0% | 15.9% | 3.2% |
| Hispanic | 0.0% | 6.8% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Pickens, MS | Central, SC | United States |
| Married Population | 38.3% | 30.2% | 49.8% |
| Currently Married | 36.1% | 27.0% | 48.0% |
| Married but Separated | 2.2% | 3.2% | 1.8% |
| Single Population | 61.7% | 69.8% | 50.2% |
| Never Married | 49.1% | 55.4% | 33.8% |
| Divorced | 4.6% | 9.5% | 10.8% |
| Widowed | 7.9% | 4.9% | 5.6% |
| space5 | | | |
| Household Size | 3.06 | 2.24 | 2.60 |
| Households | 419 | 2,190 | 124,010,992 |
| Family Households | 293 | 846 | 80,755,759 |
| Married couple, w/children | 20.1% | 53.7% | 30.5% |
| Married couple, no children | 35.2% | 27.3% | 42.9% |
| Non Family Households | 126 | 1,344 | 43,255,233 |
| Single householder, w/children | 28.3% | 12.8% | 15.8% |
| Single householder, no children | 16.4% | 6.3% | 10.8% |