| | Port St. Joe, FL | Apalachicola, FL | United States |
| Population | 3,680 | 2,580 | 329,725,481 |
| Female Population | 50.2% | 51.8% | 50.5% |
| Male Population | 49.8% | 48.2% | 49.5% |
| Median Age | 50.4 | 52.2 | 38.4 |
| space3 | | | |
| Population - 2010 | 3,424 | 2,226 | 309,327,143 |
| Population - 2000 | 3,644 | 2,334 | 285,036,114 |
| Population - 1990 | 4,044 | 2,602 | 251,960,433 |
| Pop. 2000 to Now | -3.7% | 1.6% | 15.6% |
| Pop. 1990 to Now | -13.3% | -8.8% | 30.8% |
| space4 | | | |
| Population Density | 392.9 | 1,340.3 | 93.4 |
| Land Area | 9.4 | 1.9 | 3,531,905.4 |
| Water Area | 2.6 | 0.7 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Port St. Joe, FL | Apalachicola, FL | United States |
| Age 0 to 4 | 6.8% | 2.9% | 5.9% |
| Age 5 to 9 | 7.2% | 4.3% | 6.1% |
| Age 10 to 14 | 7.8% | 2.1% | 6.6% |
| Age 15 to 17 | 2.0% | 1.1% | 3.9% |
| Age 18 to 20 | 2.6% | 2.2% | 4.0% |
| Age 21 to 24 | 0.4% | 0.9% | 5.2% |
| Age 25 to 34 | 12.6% | 16.3% | 13.8% |
| Age 35 to 44 | 7.2% | 10.1% | 12.9% |
| Age 45 to 54 | 9.8% | 12.5% | 12.6% |
| Age 55 to 59 | 12.9% | 10.1% | 6.7% |
| Age 60 to 64 | 7.7% | 10.0% | 6.3% |
| Age 65 to 74 | 11.1% | 16.6% | 9.6% |
| Age 75 to 84 | 11.6% | 7.9% | 4.5% |
| Age 85 and over | 0.3% | 2.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Port St. Joe, FL | Apalachicola, FL | United States |
| White | 77.9% | 68.0% | 59.4% |
| Black | 15.5% | 24.1% | 12.2% |
| Asian | 0.5% | 1.0% | 5.6% |
| Native American | 0.0% | 0.0% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.4% | 0.0% | 0.4% |
| Two or More Races | 2.4% | 2.8% | 3.2% |
| Hispanic | 3.3% | 4.1% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Port St. Joe, FL | Apalachicola, FL | United States |
| Married Population | 52.2% | 37.0% | 49.8% |
| Currently Married | 51.5% | 34.7% | 48.0% |
| Married but Separated | 0.7% | 2.4% | 1.8% |
| Single Population | 47.8% | 63.0% | 50.2% |
| Never Married | 24.0% | 33.5% | 33.8% |
| Divorced | 15.1% | 17.0% | 10.8% |
| Widowed | 8.7% | 12.5% | 5.6% |
| space5 | | | |
| Household Size | 2.27 | 2.14 | 2.60 |
| Households | 1,555 | 1,199 | 124,010,992 |
| Family Households | 999 | 635 | 80,755,759 |
| Married couple, w/children | 29.9% | 8.7% | 30.5% |
| Married couple, no children | 43.3% | 50.2% | 42.9% |
| Non Family Households | 556 | 564 | 43,255,233 |
| Single householder, w/children | 18.4% | 14.0% | 15.8% |
| Single householder, no children | 8.3% | 27.1% | 10.8% |