| | Salem, MO | Holbrook, NY | United States |
| Population | 4,623 | 26,958 | 329,725,481 |
| Female Population | 55.9% | 52.9% | 50.5% |
| Male Population | 44.2% | 47.1% | 49.5% |
| Median Age | 44.6 | 40.4 | 38.4 |
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| Population - 2010 | 4,954 | 26,981 | 309,327,143 |
| Population - 2000 | 4,854 | 27,512 | 285,036,114 |
| Population - 1990 | 4,486 | 25,273 | 251,960,433 |
| Pop. 2000 to Now | 0.4% | -6.2% | 15.6% |
| Pop. 1990 to Now | 8.7% | 2.1% | 30.8% |
| space4 | | | |
| Population Density | 1,456.1 | 3,757.7 | 93.4 |
| Land Area | 3.2 | 7.2 | 3,531,905.4 |
| Water Area | 0.0 | 0.0 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | Salem, MO | Holbrook, NY | United States |
| Age 0 to 4 | 7.9% | 5.6% | 5.9% |
| Age 5 to 9 | 7.2% | 5.7% | 6.1% |
| Age 10 to 14 | 2.2% | 6.4% | 6.6% |
| Age 15 to 17 | 3.9% | 4.6% | 3.9% |
| Age 18 to 20 | 4.3% | 3.3% | 4.0% |
| Age 21 to 24 | 6.3% | 4.4% | 5.2% |
| Age 25 to 34 | 7.4% | 13.9% | 13.8% |
| Age 35 to 44 | 11.5% | 12.2% | 12.9% |
| Age 45 to 54 | 11.9% | 13.6% | 12.6% |
| Age 55 to 59 | 7.3% | 7.1% | 6.7% |
| Age 60 to 64 | 6.3% | 7.6% | 6.3% |
| Age 65 to 74 | 12.1% | 10.1% | 9.6% |
| Age 75 to 84 | 8.5% | 4.5% | 4.5% |
| Age 85 and over | 3.2% | 0.9% | 1.9% |
| space1 | | | |
| Race | | | |
| | Salem, MO | Holbrook, NY | United States |
| White | 91.5% | 76.1% | 59.4% |
| Black | 0.4% | 4.2% | 12.2% |
| Asian | 0.0% | 3.7% | 5.6% |
| Native American | 0.2% | 0.2% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.3% | 0.4% |
| Two or More Races | 5.8% | 1.3% | 3.2% |
| Hispanic | 2.1% | 14.3% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Salem, MO | Holbrook, NY | United States |
| Married Population | 43.6% | 52.9% | 49.8% |
| Currently Married | 42.6% | 51.8% | 48.0% |
| Married but Separated | 0.9% | 1.1% | 1.8% |
| Single Population | 56.4% | 47.1% | 50.2% |
| Never Married | 23.2% | 33.1% | 33.8% |
| Divorced | 21.1% | 8.8% | 10.8% |
| Widowed | 12.2% | 5.2% | 5.6% |
| space5 | | | |
| Household Size | 2.09 | 3.01 | 2.60 |
| Households | 2,161 | 8,946 | 124,010,992 |
| Family Households | 1,150 | 6,722 | 80,755,759 |
| Married couple, w/children | 24.0% | 34.0% | 30.5% |
| Married couple, no children | 35.7% | 42.8% | 42.9% |
| Non Family Households | 1,011 | 2,224 | 43,255,233 |
| Single householder, w/children | 27.9% | 11.0% | 15.8% |
| Single householder, no children | 12.4% | 12.2% | 10.8% |