| | San Angelo, TX | Midland, TX | United States |
| Population | 99,401 | 130,765 | 329,725,481 |
| Female Population | 49.9% | 48.4% | 50.5% |
| Male Population | 50.1% | 51.6% | 49.5% |
| Median Age | 34.2 | 31.3 | 38.4 |
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| Population - 2010 | 93,627 | 111,272 | 309,327,143 |
| Population - 2000 | 88,439 | 94,996 | 285,036,114 |
| Population - 1990 | 84,474 | 89,443 | 251,960,433 |
| Pop. 2000 to Now | 14.9% | 54.8% | 15.6% |
| Pop. 1990 to Now | 20.3% | 64.4% | 30.8% |
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| Population Density | 1,657.9 | 1,758.2 | 93.4 |
| Land Area | 60.0 | 74.4 | 3,531,905.4 |
| Water Area | 2.3 | 0.2 | 264,836.8 |
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| Est. Total Population By Age | | | |
| | San Angelo, TX | Midland, TX | United States |
| Age 0 to 4 | 6.4% | 8.8% | 5.9% |
| Age 5 to 9 | 5.8% | 8.4% | 6.1% |
| Age 10 to 14 | 7.1% | 7.1% | 6.6% |
| Age 15 to 17 | 3.9% | 3.8% | 3.9% |
| Age 18 to 20 | 6.6% | 3.5% | 4.0% |
| Age 21 to 24 | 6.3% | 5.6% | 5.2% |
| Age 25 to 34 | 15.0% | 18.7% | 13.8% |
| Age 35 to 44 | 12.2% | 14.0% | 12.9% |
| Age 45 to 54 | 10.3% | 10.5% | 12.6% |
| Age 55 to 59 | 5.7% | 4.9% | 6.7% |
| Age 60 to 64 | 5.3% | 4.8% | 6.3% |
| Age 65 to 74 | 8.8% | 5.5% | 9.6% |
| Age 75 to 84 | 4.4% | 2.9% | 4.5% |
| Age 85 and over | 2.2% | 1.5% | 1.9% |
| space1 | | | |
| Race | | | |
| | San Angelo, TX | Midland, TX | United States |
| White | 48.1% | 41.7% | 59.4% |
| Black | 4.4% | 7.2% | 12.2% |
| Asian | 1.4% | 2.0% | 5.6% |
| Native American | 0.1% | 0.3% | 0.6% |
| Hawaiian, Pacific Islander | 0.1% | 0.0% | 0.2% |
| Other | 0.2% | 0.1% | 0.4% |
| Two or More Races | 2.0% | 2.0% | 3.2% |
| Hispanic | 43.8% | 46.5% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | San Angelo, TX | Midland, TX | United States |
| Married Population | 47.1% | 57.0% | 49.8% |
| Currently Married | 45.3% | 55.1% | 48.0% |
| Married but Separated | 1.8% | 1.9% | 1.8% |
| Single Population | 52.9% | 43.0% | 50.2% |
| Never Married | 34.7% | 28.6% | 33.8% |
| Divorced | 12.7% | 9.9% | 10.8% |
| Widowed | 5.5% | 4.5% | 5.6% |
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| Household Size | 2.46 | 2.57 | 2.60 |
| Households | 38,086 | 50,371 | 124,010,992 |
| Family Households | 23,356 | 34,336 | 80,755,759 |
| Married couple, w/children | 31.6% | 39.9% | 30.5% |
| Married couple, no children | 41.1% | 34.7% | 42.9% |
| Non Family Households | 14,730 | 16,035 | 43,255,233 |
| Single householder, w/children | 17.4% | 18.3% | 15.8% |
| Single householder, no children | 9.9% | 7.0% | 10.8% |