| | Santa Fe, TX | North Port, FL | United States |
| Population | 12,782 | 74,131 | 329,725,481 |
| Female Population | 51.4% | 52.3% | 50.5% |
| Male Population | 48.6% | 47.7% | 49.5% |
| Median Age | 45.1 | 48.5 | 38.4 |
| space3 | | | |
| Population - 2010 | 12,299 | 57,392 | 309,327,143 |
| Population - 2000 | 9,548 | 22,797 | 285,036,114 |
| Population - 1990 | 8,429 | 11,973 | 251,960,433 |
| Pop. 2000 to Now | 41.0% | 223.5% | 15.6% |
| Pop. 1990 to Now | 59.7% | 515.9% | 30.8% |
| space4 | | | |
| Population Density | 734.7 | 744.9 | 93.4 |
| Land Area | 17.4 | 99.5 | 3,531,905.4 |
| Water Area | 0.2 | 4.6 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Santa Fe, TX | North Port, FL | United States |
| Age 0 to 4 | 5.0% | 4.7% | 5.9% |
| Age 5 to 9 | 4.5% | 5.1% | 6.1% |
| Age 10 to 14 | 3.0% | 5.4% | 6.6% |
| Age 15 to 17 | 3.6% | 3.4% | 3.9% |
| Age 18 to 20 | 2.5% | 4.3% | 4.0% |
| Age 21 to 24 | 6.4% | 4.5% | 5.2% |
| Age 25 to 34 | 9.7% | 9.0% | 13.8% |
| Age 35 to 44 | 15.2% | 8.5% | 12.9% |
| Age 45 to 54 | 11.9% | 12.9% | 12.6% |
| Age 55 to 59 | 9.0% | 8.2% | 6.7% |
| Age 60 to 64 | 11.2% | 6.9% | 6.3% |
| Age 65 to 74 | 9.7% | 17.0% | 9.6% |
| Age 75 to 84 | 7.0% | 8.0% | 4.5% |
| Age 85 and over | 1.2% | 2.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Santa Fe, TX | North Port, FL | United States |
| White | 75.2% | 79.0% | 59.4% |
| Black | 0.0% | 5.4% | 12.2% |
| Asian | 0.2% | 1.9% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.1% | 0.4% |
| Two or More Races | 6.9% | 2.9% | 3.2% |
| Hispanic | 17.7% | 10.8% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Santa Fe, TX | North Port, FL | United States |
| Married Population | 55.8% | 57.2% | 49.8% |
| Currently Married | 54.9% | 56.2% | 48.0% |
| Married but Separated | 0.9% | 0.9% | 1.8% |
| Single Population | 44.2% | 42.8% | 50.2% |
| Never Married | 24.4% | 23.4% | 33.8% |
| Divorced | 12.6% | 14.3% | 10.8% |
| Widowed | 7.2% | 5.2% | 5.6% |
| space5 | | | |
| Household Size | 2.62 | 2.62 | 2.60 |
| Households | 4,879 | 28,209 | 124,010,992 |
| Family Households | 3,415 | 21,424 | 80,755,759 |
| Married couple, w/children | 25.8% | 19.6% | 30.5% |
| Married couple, no children | 59.8% | 57.5% | 42.9% |
| Non Family Households | 1,464 | 6,785 | 43,255,233 |
| Single householder, w/children | 8.9% | 14.6% | 15.8% |
| Single householder, no children | 5.5% | 8.3% | 10.8% |