| | Duck Key, FL | Orlando, FL | United States |
| Population | 783 | 302,968 | 329,725,481 |
| Female Population | 37.2% | 51.5% | 50.5% |
| Male Population | 62.8% | 48.5% | 49.5% |
| Median Age | 62.9 | 34.4 | 38.4 |
| space3 | | | |
| Population - 2010 | 699 | 239,219 | 309,327,143 |
| Population - 2000 | 443 | 185,951 | 285,036,114 |
| Population - 1990 | 1,077 | 164,693 | 251,960,433 |
| Pop. 2000 to Now | 58.0% | 55.7% | 15.6% |
| Pop. 1990 to Now | -35.0% | 75.8% | 30.8% |
| space4 | | | |
| Population Density | 1,307.2 | 2,751.2 | 93.4 |
| Land Area | 0.6 | 110.1 | 3,531,905.4 |
| Water Area | 0.0 | 8.7 | 264,836.8 |
| space | | | |
| Est. Total Population By Age | | | |
| | Duck Key, FL | Orlando, FL | United States |
| Age 0 to 4 | 4.6% | 6.7% | 5.9% |
| Age 5 to 9 | 1.0% | 5.8% | 6.1% |
| Age 10 to 14 | 1.3% | 5.3% | 6.6% |
| Age 15 to 17 | 0.0% | 3.4% | 3.9% |
| Age 18 to 20 | 0.0% | 2.5% | 4.0% |
| Age 21 to 24 | 4.7% | 5.5% | 5.2% |
| Age 25 to 34 | 2.3% | 22.0% | 13.8% |
| Age 35 to 44 | 4.6% | 16.0% | 12.9% |
| Age 45 to 54 | 7.4% | 12.0% | 12.6% |
| Age 55 to 59 | 8.2% | 5.7% | 6.7% |
| Age 60 to 64 | 26.2% | 4.6% | 6.3% |
| Age 65 to 74 | 26.1% | 6.6% | 9.6% |
| Age 75 to 84 | 11.0% | 2.8% | 4.5% |
| Age 85 and over | 2.7% | 1.1% | 1.9% |
| space1 | | | |
| Race | | | |
| | Duck Key, FL | Orlando, FL | United States |
| White | 82.1% | 35.0% | 59.4% |
| Black | 5.9% | 22.5% | 12.2% |
| Asian | 2.7% | 3.9% | 5.6% |
| Native American | 0.0% | 0.1% | 0.6% |
| Hawaiian, Pacific Islander | 0.0% | 0.0% | 0.2% |
| Other | 0.0% | 0.9% | 0.4% |
| Two or More Races | 0.0% | 3.5% | 3.2% |
| Hispanic | 9.3% | 34.2% | 18.4% |
| space2 | | | |
| Marriage & Family | | | |
| | Duck Key, FL | Orlando, FL | United States |
| Married Population | 59.9% | 40.2% | 49.8% |
| Currently Married | 59.9% | 37.8% | 48.0% |
| Married but Separated | 0.0% | 2.4% | 1.8% |
| Single Population | 40.1% | 59.8% | 50.2% |
| Never Married | 15.5% | 43.2% | 33.8% |
| Divorced | 17.0% | 12.7% | 10.8% |
| Widowed | 7.5% | 3.9% | 5.6% |
| space5 | | | |
| Household Size | 2.19 | 2.53 | 2.60 |
| Households | 294 | 118,834 | 124,010,992 |
| Family Households | 200 | 65,783 | 80,755,759 |
| Married couple, w/children | 3.0% | 29.9% | 30.5% |
| Married couple, no children | 84.0% | 34.0% | 42.9% |
| Non Family Households | 94 | 53,051 | 43,255,233 |
| Single householder, w/children | 11.5% | 20.8% | 15.8% |
| Single householder, no children | 1.5% | 15.3% | 10.8% |